| Long name: |
human Fibrinogen (4F7) Monoclonal Antibody |
| Also known as: |
human Fibrinogen (4F7) Monoclonal Antibody |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
human Fibrinogen |
| Specificity: |
This is a highly specific antibody against human Fibrinogen |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Monoclonal |
| Clone number: |
4F7 |
| Concentration: |
1ug per 1ul |
| Source: |
Fibrinogen from human plasma |
| Gene ID number: |
2243 |
| Tested Applications: |
IF(IHC-P), IHC-P |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500) |
| Cross reactivity: |
Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
All chains are connected with each other by a number of disulfide bonds, All these facts make fibrinogen an important parameter in the diagnosis of cardiovascular diseases, An increase in blood fibrinogen concentration was shown to be a strong predictor of coronary heart disease (Sonel A, Fibrinogen activation is also involved in pathogenesis of inflammation, Fibrinogen clotting underlies pathogenesis of MI, Fibrinopeptides A (1 to 16 amino acids) and B (1 to 17 amino acids) are released by thrombin from the N terminal parts of alpha and beta chains, In this way fibrinogen is converted into fibrin, It is a large protein and it consists of two identical subunits that contain three polypeptide chains: alpha, The elevated level of fibrinogen in patient's blood is regarded as an independent risk factor for cardiovascular diseases, The normal fibrinogen concentration in plasma is about 3 mg/ml, and Rapold H, beta and gamma, et al, et al), respectively, since fibrin is the main substrate for thrombus formation, thromboembolism and thromboses of arteries and veins, tumor growth and many other diseases, which by means of polymerization forms a fibrin clot, Fibrinogen is the main protein of blood coagulation system, J |
| Purification method: |
Purified by Protein G |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
FGA protein, FGB, FGG, FIBA_HUMAN, Fib2, Fibrin alpha chain , Fibrinogen A alpha polypeptide chain, Fibrinogen B alpha polypeptide, Fibrinogen G alpha polypeptide, Fibrinogen alpha chain, Fibrinogen beta chain, Fibrinogen gamma chain, MGC104327, MGC119422, MGC119423, MGC119425, MGC120405, FGA, Fibrinogen A alpha polypeptide |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target: |
Fibrinogen (4F7) Monoclonal |
| Short name: |
human Fibrinogen (4F7) Monoclonal Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens Fibrinogen (4F7) monoclonal (Antibody to), H |
| Alternative technique: |
antibodies |