| Long name: |
ALEXA FLUOR 488 Conjugated, human Fibrinogen (4F7) Monoclonal Antibody |
| Also known as: |
Anti-human Fibrinogen MAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Mouse (Mus musculus) |
| Target Antigen: |
human Fibrinogen |
| Specificity: |
This is a highly specific antibody against human Fibrinogen |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Monoclonal |
| Clone: |
4F7 |
| Concentration: |
1ug per 1ul |
| Source: |
Fibrinogen from human plasma |
| Gene ID Number: |
2243 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
All chains are connected with each other by a number of disulfide bonds, All these facts make fibrinogen an important parameter in the diagnosis of cardiovascular diseases, An increase in blood fibrinogen concentration was shown to be a strong predictor of coronary heart disease (Sonel A, Fibrinogen activation is also involved in pathogenesis of inflammation, Fibrinogen clotting underlies pathogenesis of MI, Fibrinopeptides A (1 to 16 amino acids) and B (1 to 17 amino acids) are released by thrombin from the N terminal parts of alpha and beta chains, In this way fibrinogen is converted into fibrin, It is a large protein and it consists of two identical subunits that contain three polypeptide chains: alpha, The elevated level of fibrinogen in patient's blood is regarded as an independent risk factor for cardiovascular diseases, The normal fibrinogen concentration in plasma is about 3 mg/ml, and Rapold H, beta and gamma, et al, et al), respectively, since fibrin is the main substrate for thrombus formation, thromboembolism and thromboses of arteries and veins, tumor growth and many other diseases, which by means of polymerization forms a fibrin clot, Fibrinogen is the main protein of blood coagulation system, J |
| Purification: |
Purified by Protein G |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
FGA protein, FGB, FGG, FIBA_HUMAN, Fib2, Fibrin alpha chain , Fibrinogen A alpha polypeptide chain, Fibrinogen B alpha polypeptide, Fibrinogen G alpha polypeptide, Fibrinogen alpha chain, Fibrinogen beta chain, Fibrinogen gamma chain, MGC104327, MGC119422, MGC119423, MGC119425, MGC120405, FGA, Fibrinogen A alpha polypeptide |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the human Fibrinogen (4F7) Monoclonal Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target: |
Fibrinogen (4F7) Monoclonal |
| Short name: |
human Fibrinogen (4F7) Monoclonal Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, sapiens Fibrinogen (4F7) monoclonal (Antibody to), H |
| Alternative technique: |
antibodies |