| Also known as: |
ZAP 70 |
| Other names: |
70 kDa zeta-associated protein, 70 kDa zeta-chain associated protein, 70 kDa zeta-chain associated protein, 70kD, Syk-related tyrosine kinase, Tyrosine-protein kinase ZAP-70, syk-related tyrosine kinase, tyrosine-protein kinase ZAP-70, zeta-chain (TCR) associated protein kinase 70kDa, zeta-chain associated protein kinase, tyrosine-protein kinase ZAP-70 isoform 1 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
ZAP 70 |
| Other gene names: |
SRK, SRK, STCD, STD, TZK, ZAP-70, ZAP70, ZAP70 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
ZAP-03 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Recent studies suggest that ZAP-70 is also expressed in a population of normal immature B-cells and in B-cells from a sub-set of patients with chronic lymphocytic leukaemia, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, ZAP-70 is primarily expressed in T lymphocytes and natural killer cells, a 70kD tyrosine protein kinase which associates with the T-cell receptor (TCR) zeta chain and undergoes phosphorylation following TCR stimulation, where it plays a key role in T-cell receptor (TCR) signalling, ZAP 70 Recognises human ZAP-70 |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0mg/ml, IgG concentration 1 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
Flow Cytometry (FACS), Western Blot (WB) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
ZAP 70 |
| Short name: |
MOUSE Anti-HUMAN ZAP 70 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens ZAP 70 (Antibody to), MOUSE antibody to-H |
| Alternative technique: |
antibodies |
| Identity: |
17798 |
| Gene: |
YLPM1 |
More about : YLPM1 |
| Long gene name: |
YLP motif containing 1 |
| Synonyms gene: |
C14orf170 |
| Synonyms gene name: |
chromosome 14 open reading frame 170 |
| Synonyms: |
ZAP PPP1R169 |
| Synonyms name: |
protein phosphatase 1, regulatory subunit 169 |
| Locus: |
14q24, 3 |
| Discovery year: |
2003-11-21 |
| GenBank acession: |
AK090435 |
| Entrez gene record: |
56252 |
| Pubmed identfication: |
7596406 |
| RefSeq identity: |
NM_019589 |
| Classification: |
Protein phosphatase 1 regulatory subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000172503 |