| Also known as: |
ZAP 70 |
| Other names: |
70 kDa zeta-associated protein, 70 kDa zeta-chain associated protein, 70 kDa zeta-chain associated protein, 70kD, Syk-related tyrosine kinase, Tyrosine-protein kinase ZAP-70, syk-related tyrosine kinase, tyrosine-protein kinase ZAP-70, zeta-chain (TCR) associated protein kinase 70kDa, zeta-chain associated protein kinase, tyrosine-protein kinase ZAP-70 isoform 1 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
ZAP 70 |
| Other gene names: |
SRK, SRK, STCD, STD, TZK, ZAP-70, ZAP70, ZAP70 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
SBZAP |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Recent studies suggest that ZAP-70 is also expressed in a population of normal immature B-cells and in B-cells from a sub-set of patients with chronic lymphocytic leukaemia, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, ZAP-70 is primarily expressed in T lymphocytes and natural killer cells, a 70kDa tyrosine protein kinase which associates with the T-cell receptor (TCR) zeta chain and undergoes phosphorylation following TCR stimulation, where it plays a key role in T-cell receptor (TCR) signalling, ZAP 70 This item recognises human ZAP-70 |
| Form/Appearance: |
FITC (Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid) |
| Concentration: |
1 miligram per 1 mililiter, IgG concentration 0 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody is photosensitive and should be protected from light, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
Flow Cytometry (FACS) |
| Properties: |
FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, MBS mono FITC is highly sensitive to pH extremes, This MBS mono Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Conjugation: |
Anti-FITC Antibody |
| Gene target: |
ZAP 70: |
| Short name: |
MOUSE Anti-HUMAN ZAP 70:FITC Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, Antibody |
| Label: |
FITC |
| Alternative name: |
sapiens ZAP 70:fluorecein (Antibody to), MOUSE antibody to-H |
| Alternative technique: |
antibodies |
| Identity: |
17798 |
| Gene: |
YLPM1 |
More about : YLPM1 |
| Long gene name: |
YLP motif containing 1 |
| Synonyms gene: |
C14orf170 |
| Synonyms gene name: |
chromosome 14 open reading frame 170 |
| Synonyms: |
ZAP PPP1R169 |
| Synonyms name: |
protein phosphatase 1, regulatory subunit 169 |
| Locus: |
14q24, 3 |
| Discovery year: |
2003-11-21 |
| GenBank acession: |
AK090435 |
| Entrez gene record: |
56252 |
| Pubmed identfication: |
7596406 |
| RefSeq identity: |
NM_019589 |
| Classification: |
Protein phosphatase 1 regulatory subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000172503 |