| Also known as: |
Ku80 |
| Other names: |
80kDa, 86 kDa subunit of Ku antigen, 86 kDa subunit of Ku antigen, ATP-dependent DNA helicase 2 subunit 2, ATP-dependent DNA helicase 2 subunit 2, ATP-dependent DNA helicase II 80 kDa subunit, ATP-dependent DNA helicase II 80 kDa subunit, CTC box-binding factor 85 kDa subunit, CTC box-binding factor 85 kDa subunit, CTC85, CTC85, CTCBF, CTCBF, DNA repair protein XRCC5, DNA repair protein XRCC5, Ku autoantigen, Ku80, Ku86, Ku86 autoantigen related protein 1, Lupus Ku autoantigen protein p86, Nuclear factor IV, TLAA, TLAA, Thyroid-lupus autoantigen, X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining), X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining), X-ray repair cross-complementing protein 5, X-ray repair cross-complementing protein 5, lupus Ku autoantigen protein p86, nuclear factor IV, thyroid-lupus autoantigen, X-ray repair cross-complementing protein 5 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
Ku80 |
| Other gene names: |
CTC85, CTCBF, G22P2, KARP-1, KARP1, KU80, KUB2, Ku86, NFIV, TLAA, XRCC5, XRCC5 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2a |
| Clone: |
MEM-54 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
DNA bound Ku recruits the large catalytic subunit DNA-PKcs to form the DNA-dependent protein kinase complex DNA-PK, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_The Ku protein, _x000D__x000D_This item is reported as suitable for use in immunocytochemistry, an evolutionarily conserved nuclear ATP-dependent DNA helicase, exists as a tightly associated heterodimer consisting of a 70kDa (Ku70) and 80kDa (Ku80) subunit which binds to DNA double-strand break ends (DSB), facilitating DNA repair by the non-homologous end-joining (NHEJ) pathway, involved in a major proportion of DNA repair and in V(D)J recombination, originally described as an autoantigen, Ku80 This item specifically recognises the 80kDa subunit of human Ku protein |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0mg/ml, IgG concentration 1 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
Immunoprecipitation (IP), Western Blot (WB) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
Ku80 |
| Short name: |
MOUSE Anti-HUMAN Ku80 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens Ku80 (Antibody to), MOUSE antibody to-H |
| Alternative technique: |
antibodies |
| Identity: |
12833 |
| Gene: |
XRCC5 |
More about : XRCC5 |
| Long gene name: |
X-ray repair cross complementing 5 |
| Synonyms gene name: |
80kD) , Ku autoantigen, X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining |
| Synonyms: |
KU80 KARP-1 Ku86 KUB2 |
| Synonyms name: |
80kDa , Ku autoantigen |
| Locus: |
2q35 |
| Discovery year: |
1992-01-22 |
| GenBank acession: |
AF039597 |
| Entrez gene record: |
7520 |
| Pubmed identfication: |
9636207 9214634 |
| RefSeq identity: |
NM_021141 |
| Havana BLAST/BLAT: |
OTTHUMG00000133059 |