| known also as: |
Anti-GOAT ANTI HUMAN Ku80 |
| known also as: |
Caprine ANTI HUMAN Ku80 |
| known also as: |
Caprinae ANTI Homo sapiens Ku80 |
| known also as: |
Ku80 |
| Other names: |
80kDa, 86 kDa subunit of Ku antigen, 86 kDa subunit of Ku antigen, ATP-dependent DNA helicase 2 subunit 2, ATP-dependent DNA helicase 2 subunit 2, ATP-dependent DNA helicase II 80 kDa subunit, ATP-dependent DNA helicase II 80 kDa subunit, CTC box-binding factor 85 kDa subunit, CTC box-binding factor 85 kDa subunit, CTC85, CTC85, CTCBF, CTCBF, DNA repair protein XRCC5, DNA repair protein XRCC5, Ku autoantigen, Ku80, Ku86, Ku86 autoantigen related protein 1, Lupus Ku autoantigen protein p86, Nuclear factor IV, TLAA, TLAA, Thyroid-lupus autoantigen, X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining), X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining), X-ray repair cross-complementing protein 5, X-ray repair cross-complementing protein 5, lupus Ku autoantigen protein p86, nuclear factor IV, thyroid-lupus autoantigen, X-ray repair cross-complementing protein 5 |
| Gene name: |
Ku80 |
| Other gene names: |
CTC85, CTCBF, G22P2, KARP-1, KARP1, KU80, KUB2, Ku86, NFIV, TLAA, XRCC5, XRCC5 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Goat |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
DNA bound Ku recruits the large catalytic subunit DNA-PKcs to form the DNA-dependent protein kinase complex DNA-PK, _x000D__x000D_The Ku protein, an evolutionarily conserved nuclear ATP-dependent DNA helicase, exists as a tightly associated heterodimer consisting of a 70kDa (Ku70) and 80kDa (Ku80) subunit which binds to DNA double-strand break ends (DSB), facilitating DNA repair by the non-homologous end-joining (NHEJ) pathway, involved in a major proportion of DNA repair and in V(D)J recombination, originally described as an autoantigen, Ku80 This item specifically recognises the 80kDa subunit of human Ku protein |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
IgG concentration 500ug/1000ul |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
Western Blot (WB), ELISA (EIA) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
Ku80 |
| Short name: |
GOAT ANTI HUMAN Ku80 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens Ku80 (Antibody to), caprine antibody to H |
| Alternative technique: |
antibodies |
| Identity: |
12833 |
| Gene: |
XRCC5 |
More about : XRCC5 |
| Long gene name: |
X-ray repair cross complementing 5 |
| Synonyms gene name: |
80kD) , Ku autoantigen, X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining |
| Synonyms: |
KU80 KARP-1 Ku86 KUB2 |
| Synonyms name: |
80kDa , Ku autoantigen |
| Locus: |
2q35 |
| Discovery year: |
1992-01-22 |
| GenBank acession: |
AF039597 |
| Entrez gene record: |
7520 |
| Pubmed identfication: |
9636207 9214634 |
| RefSeq identity: |
NM_021141 |
| Havana BLAST/BLAT: |
OTTHUMG00000133059 |