| Also known as: |
XRCC5 / Ku80 |
| Other names: |
80kDa, 86 kDa subunit of Ku antigen, 86 kDa subunit of Ku antigen, ATP-dependent DNA helicase 2 subunit 2, ATP-dependent DNA helicase 2 subunit 2, ATP-dependent DNA helicase II 80 kDa subunit, ATP-dependent DNA helicase II 80 kDa subunit, CTC box-binding factor 85 kDa subunit, CTC box-binding factor 85 kDa subunit, CTC85, CTC85, CTCBF, CTCBF, DNA repair protein XRCC5, DNA repair protein XRCC5, Ku autoantigen, Ku80, Ku86, Ku86 autoantigen related protein 1, Lupus Ku autoantigen protein p86, Nuclear factor IV, TLAA, TLAA, Thyroid-lupus autoantigen, X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining), X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining), X-ray repair cross-complementing protein 5, X-ray repair cross-complementing protein 5, lupus Ku autoantigen protein p86, nuclear factor IV, thyroid-lupus autoantigen, X-ray repair cross-complementing protein 5 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
XRCC5 |
| Other gene names: |
CTC85, CTCBF, G22P2, KARP-1, KARP1, KU80, KUB2, Ku86, NFIV, TLAA, XRCC5, XRCC5 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG |
| Clone: |
8, 149 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, Recombinant antigen containing the carboxy terminal portion of human Ku80 protein |
| Purification method: |
Protein G Purified |
| Form/Appearance: |
No preservative added, pH 7, 4, PBS |
| Concentration: |
1 miligram per 1 mililiter |
| Storage and shipping: |
Cycles of freezing and defrosting may denaturate the polypeptide chains of the antibodies and reduce their activity, For longer storage the antibody should be kept at -20 degrees Celsius, For short term storage keep the antibody at +4 degrees Celsius |
| Tested applications:: |
Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
2 light chains, Each murine monoclonal anibody has his own affinity specific for the clone, For storage sodium azide is added or you can call us to request azide free antibody preparations, IgG, Monoclonals of this antigen are available in different clones, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, The IgG antibody has 2 , There are 2 heavy chains, These will need colder storage temperatures, They represent 70% or more of , This antibody can be antigen purified or protein A or G purified, goat polyclonal antibodies , mouse monoclonal H&, Immunoglobulin gamma, L chain clones or rabbit, antibodies, antigen , binding sites, have 4 parts, serum |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
8] XRCC5 / Ku80, Monoclonal [ 149 |
| Short name: |
8] (IgG) XRCC5 / Ku80 Antibody, Mouse Monoclonal [clone 149 |
| Technique: |
IgGs, Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
sapiens X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) / Ku80 (Antibody to), 8] (Immunoglobulin G) to H, Mouse monoclonal [clonality 149 |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BT, DNA-templated and biological process this GO :0007420 and brain development and biological process this GO :0008022 and protein C-terminus binding and molecular function this GO :0008283 and cell proliferation and biological process this GO :0016020 and membrane and cellular component this GO :0016032 and viral process and biological process this GO :0016817 and hydrolase activity, DNA-templated and biological process this GO :0050769 and positive regulation of neurogenesis and biological process this GO :0051575 and 5'-deoxyribose-5-phosphate lyase activity and molecular function this GO :0060218 and hematopoietic stem cell differentiation and biological process this GO :0070419 and nonhomolo this GO us end joining complex and cellular component this GO :0071398 and cellular response to fatty acid and biological process this GO :0071475 and cellular hyperosmotic salinity response and biological process this GO :0071481 and cellular response to X-ray and biological process this GO :0075713 and establishment of integrated proviral latency and biological process, KARP-1 and KARP1 and KU80 and Ku86 and KUB2 and NFIV, XRCC5 and IDBG-80616 and ENSG00000079246 and 7520, Xrcc5 and IDBG-165686 and ENSMUSG00000026187 and 22596, acting on acid anhydrides, acting on acid anhydrides and also this GO :0031625 : ubiquitin protein ligase binding and also this GO :0042162 : telomeric DNA binding and also this GO :0044212 : transcription regulatory region DNA binding and also this GO :0044822 : poly(A) RNA binding and also this GO :0051575 : 5'-deoxyribose-5-phosphate lyase activity, acting on acid anhydrides and molecular function this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0032481 and positive regulation of type I interferon production and biological process this GO :0032508 and DNA duplex unwinding and biological process this GO :0042162 and telomeric DNA binding and molecular function this GO :0042493 and response to drug and biological process this GO :0043234 and protein complex and cellular component this GO :0043564 and Ku70:Ku80 complex and cellular component this GO :0044212 and transcription regulatory region DNA binding and molecular function this GO :0044822 and poly(A) RNA binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0045892 and negative regulation of transcription, hydrolase activity, nuclei, telomeric region and cellular component this GO :0003677 and DNA binding and molecular function this GO :0003684 and damaged DNA binding and molecular function this GO :0003690 and double-stranded DNA binding and molecular function this GO :0003691 and double-stranded telomeric DNA binding and molecular function this GO :0004003 and ATP-dependent DNA helicase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006281 and DNA repair and biological process this GO :0006302 and double-strand break repair and biological process this GO :0006303 and double-strand break repair via nonhomolo this GO us end joining and biological process this GO :0006310 and DNA recombination and biological process this GO :0006351 and transcription, this GO :0000723 and telomere maintenance and biological process this GO :0000783 and nuclear telomere cap complex and cellular component this GO :0000784 and nuclear chromosome, this GO :0003677 : DNA binding, this GO :0003677 : DNA binding and also this GO :0003684 : damaged DNA binding and also this GO :0003690 : double-stranded DNA binding and also this GO :0003691 : double-stranded telomeric DNA binding and also this GO :0004003 : ATP-dependent DNA helicase activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0008022 : protein C-terminus binding and also this GO :0016817 : hydrolase activity, this GO :0003684 : damaged DNA binding, this GO :0003690 : double-stranded DNA binding, this GO :0003691 : double-stranded telomeric DNA binding, this GO :0004003 : ATP-dependent DNA helicase activity, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0008022 : protein C-terminus binding, this GO :0016817 : hydrolase activity, this GO :0031625 : ubiquitin protein ligase binding, this GO :0042162 : telomeric DNA binding, this GO :0044212 : transcription regulatory region DNA binding, this GO :0044822 : poly(A) RNA binding, this GO :0051575 : 5'-deoxyribose-5-phosphate lyase activity, 88138 and IDBG-643715 and ENSBTAG00000010426 and 531945, X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) |
| Identity: |
12833 |
| Gene: |
XRCC5 |
More about : XRCC5 |
| Long gene name: |
X-ray repair cross complementing 5 |
| Synonyms gene name: |
80kD) , Ku autoantigen, X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining |
| Synonyms: |
KU80 KARP-1 Ku86 KUB2 |
| Synonyms name: |
80kDa , Ku autoantigen |
| Locus: |
2q35 |
| Discovery year: |
1992-01-22 |
| GenBank acession: |
AF039597 |
| Entrez gene record: |
7520 |
| Pubmed identfication: |
9636207 9214634 |
| RefSeq identity: |
NM_021141 |
| Havana BLAST/BLAT: |
OTTHUMG00000133059 |