| Also known as: |
ATIC |
| Other names: |
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase, 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase, 5-aminoimidazole-4-carboxamide-1-beta-D-ribonucleotide transformylase/inosinicase, AICAR formyltransferase/IMP cyclohydrolase bifunctional enzyme, AICAR transformylase, AICARFT/IMPCHASE, Bifunctional purine biosynthesis protein PURH, bifunctional purine biosynthesis protein PURH, phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase, bifunctional purine biosynthesis protein PURH |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
ATIC |
| Other gene names: |
AICAR, AICARFT, ATIC, IMPCHASE, PURH, PURH, ATIC |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
F38 P7 H9 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Synthetic Peptide |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The anti-inflammatory and neuroprotective functions of ATIC, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_ATIC has been identified as an activator of AMP-activated protein kinase (AMPK), a known regulator of energy homeostasis, a ribonucleotide formyltransferase (5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase) and member of the purH family, also have implications for its use in the treatment of Alzheimer's disease, inhibitor of cell proliferation and inducer of apoptosis in cancerous cells of various origins, making ATIC a potential therapeutic agent for cancer, otherwise known as AICAR, which helps catalyze the final steps of the purine biosynthesis pathway, ATIC This item specifically recognises ATIC |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0mg/ml, IgG concentration 1 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
Western Blot (WB), Immunohistology - Paraffin (IHC) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
ATIC |
| Short name: |
MOUSE Anti-ATIC Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
MOUSE antibody to-ATIC (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
794 |
| Gene: |
ATIC |
More about : ATIC |
| Long gene name: |
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase |
| Synonyms: |
PURH AICARFT IMPCHASE |
| Synonyms name: |
phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase |
| Locus: |
2q35 |
| Discovery year: |
1997-05-15 |
| Entrez gene record: |
471 |
| Pubmed identfication: |
8567683 9378707 |
| RefSeq identity: |
NM_004044 |
| Havana BLAST/BLAT: |
OTTHUMG00000133023 |