| known also as: |
Anti-RABBIT ANTI ORAI1 (C-TERMINAL) |
| known also as: |
RABBIT ANTI ORAI1 (C-TERMINAL) |
| known also as: |
Lapin ANTI ORAI1 (C-TERMINAL) |
| known also as: |
ORAI1 |
| Other names: |
Calcium release-activated calcium channel protein 1, ORAI calcium release-activated calcium modulator 1, Protein orai-1, Transmembrane protein 142A, calcium release-activated calcium channel protein 1, calcium release-activated calcium modulator 1, protein orai-1, transmembrane protein 142A, calcium release-activated calcium channel protein 1 |
| Gene name: |
ORAI1 |
| Other gene names: |
CRACM1, CRACM1, ORAI1, ORAT1, TMEM142A, TMEM142A, ORAI1 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
(CRAC) channels, CRAC channels are the main pathway for Ca<, ORAI1 functions as a highly selective Ca<, _x000D__x000D_Antigen stimulation of immune cells triggers Ca<, _x000D__x000D_Defective ORAI1 in humans is the cause of one form of hereditary severe combined immune deficiency (SCID), _x000D__x000D_ORAI1 is a four- transmembrane spanning protein that is an essential component of CRAC, _x000D__x000D_This item is not expected to cross react with either ORAI2 or ORAI3, a 32, also known as Transmembrane protein 142A (TMEM142A), entry, entry through Ca<, influx in T-cells and promote the immune response to pathogens by activating the transcription factor NFAT, plasma membrane channel that is gated through interactions with STIM1, release-activated Ca<, sensor, the store-activated endoplasmic reticulum Ca<, which results in ablated T-cell Ca<, /sup>, /sup>, /sup>, /sup>, /sup>, /sup>, /sup>, 2+<, 2+<, 2+<, 2+<, 2+<, 2+<, 2+<, 7 kDa multi-pass membrane protein belonging to the ORAI family, ORAI1 This item recognises human ORAI1, sup>, sup>, sup>, sup>, sup>, sup>, sup> |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0mg/ml, IgG concentration 1 |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
Immunohistology - Paraffin (IHC), Western Blot (WB) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
ORAI1 |
| Short name: |
Anti-ORAI1 (C-TERMINAL) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
antibody to-ORAI1 (C-TERMINAL) (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
25896 |
| Gene: |
ORAI1 |
More about : ORAI1 |
| Long gene name: |
ORAI calcium release-activated calcium modulator 1 |
| Synonyms gene: |
TMEM142A |
| Synonyms gene name: |
transmembrane protein 142A |
| Synonyms: |
FLJ14466 CRACM1 |
| Synonyms name: |
calcium release-activated calcium modulator 1 |
| Locus: |
12q24, 31 |
| Discovery year: |
2006-04-10 |
| GenBank acession: |
AK027372 |
| Entrez gene record: |
84876 |
| Pubmed identfication: |
16582901 |
| RefSeq identity: |
NM_032790 |
| Classification: |
ORAI calcium release-activated calcium modulators |
| Havana BLAST/BLAT: |
OTTHUMG00000169073 |
| Locus Specific Databases: |
ORAI1base: Mutation registry for severe combined immunodeficiency LRG_93 |