| known also as: |
Anti-RABBIT ANTI 14-3-3 EPSILON (N-TERMINAL) |
| known also as: |
RABBIT ANTI 14-3-3 EPSILON (N-TERMINAL) |
| known also as: |
Lapin ANTI 14-3-3 EPSILON (N-TERMINAL) |
| known also as: |
14-3-3 EPSILON |
| Other names: |
14-3-3 protein epsilon, N/A, N/A, Protein kinase C inhibitor protein 1, 14-3-3 protein epsilon |
| Gene name: |
14-3-3 EPSILON |
| Other gene names: |
14-3-3E, KCIP-1, N/A, YWHAE, N/A |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Sheep |
| Specificity and cross-reactivity: |
14-3-3 epsilon is expressed in all mammals, 14-3-3 epsilon is thought to deactivate heat shock factor 1 in cells recovering from heat shock, It is a member of the 14-3-3 family which consists of 30 kDa proteins that are involved in multiple protein kinase signalling pathways, It is also a potential suicide susceptibility gene, It is deleted in small cell lung cancers disrupting the G checkpoint During apoptosis, Protein interactions with 14-3-3 show distinct preference for its different isoforms and are regulated by phosphorylation of both 14-3-3 and the bound protein, This item may not react with recombinant proteins that are not N-acetylated, When bound by ERK, cleavage of 14-3-3 protein by caspase-3 increases the affinity between bad and Bcl-x(L), cytoskeletal structure, intracellular trafficking and targeting, regulation of cell cycle progression, transcription, 14-3-3 EPSILON This item recognises the acetylated N-terminal of 14-3-3 epsilon |
| Form/Appearance: |
Serum (Serum - liquid) |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
ELISA (EIA), Immunohistology - Paraffin (IHC), Western Blot (WB) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
14-3-3 EPSILON |
| Short name: |
Anti-14-3-3 EPSILON (N-TERMINAL) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
antibody to-14-3-3 EPSILON (N-TERMINAL) (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
12854 |
| Gene: |
YWHAQ |
More about : YWHAQ |
| Long gene name: |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta |
| Synonyms gene name: |
theta , theta polypeptide protein, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein |
| Synonyms: |
HS1 14-3-3 |
| Synonyms name: |
protein tau |
| Locus: |
2p25, 1 |
| Discovery year: |
1999-08-20 |
| GenBank acession: |
AF070556 |
| Entrez gene record: |
10971 |
| Pubmed identfication: |
11080204 |
| RefSeq identity: |
NM_006826 |
| Classification: |
14-3-3 phospho-serine/phospho-threonine binding proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000013848 |