| Long name: |
Biotin Conjugated, CACNA1S Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CACNA1S |
| Specificity: |
This is a highly specific antibody against CACNA1S |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
951-1001/1873 |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human CACNA1S |
| Gene ID number: |
779 |
| Swiss Prot: |
Q13698 |
| Tested applications: |
IHC-P |
| Recommended dilutions: |
IHC-P(1:100-500) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Calcium channels containing the alpha-1S subunit play an important role in excitation-contraction coupling in skeletal muscle, Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group, The isoform alpha-1S gives rise to L-type calcium currents, They are blocked by dihydropyridines (DHP), They are however insensitive to omega-conotoxin-GVIA (omega-CTx-GVIA) and omega-agatoxin-IVA (omega-Aga-IVA), and by omega-agatoxin-IIIA (omega-Aga-IIIA), benzothiazepines, cell division and cell death, cell motility, gene expression, hormone or neurotransmitter release, including muscle contraction, phenylalkylamines, Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
Cav1, 1 hypoPP |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CACNA1S Conjugated |
| Short name: |
Conjugated, CACNA1S Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, CACNA1S (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
1397 |
| Gene: |
CACNA1S |
More about : CACNA1S |
| Long gene name: |
calcium voltage-gated channel subunit alpha1 S |
| Synonyms gene: |
HOKPP MHS5 CACNL1A3 |
| Synonyms gene name: |
L type, alpha 1S subunit , calcium channel, voltage-dependent |
| Locus: |
1q32, 1 |
| Discovery year: |
1992-03-27 |
| GenBank acession: |
L33798 |
| Entrez gene record: |
779 |
| Pubmed identfication: |
7916735 16382099 |
| RefSeq identity: |
NM_000069 |
| Classification: |
Calcium voltage-gated channel subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000035784 |
| Locus Specific Databases: |
LOVD - Leiden Open Variation Database |