| Long name: |
ALEXA FLUOR 488 Conjugated, CACNA1S Polyclonal Antibody |
| Also known as: |
Anti-CACNA1S PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CACNA1S |
| Specificity: |
This is a highly specific antibody against CACNA1S |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
951-1001/1873 |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CACNA1S |
| Gene ID Number: |
779 |
| Swiss Prot: |
Q13698 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Calcium channels containing the alpha-1S subunit play an important role in excitation-contraction coupling in skeletal muscle, Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group, The isoform alpha-1S gives rise to L-type calcium currents, They are blocked by dihydropyridines (DHP), They are however insensitive to omega-conotoxin-GVIA (omega-CTx-GVIA) and omega-agatoxin-IVA (omega-Aga-IVA), and by omega-agatoxin-IIIA (omega-Aga-IIIA), benzothiazepines, cell division and cell death, cell motility, gene expression, hormone or neurotransmitter release, including muscle contraction, phenylalkylamines, Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
Cav1, 1 hypoPP |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the CACNA1S Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
CACNA1S |
| Short name: |
CACNA1S Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, CACNA1S (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
1397 |
| Gene: |
CACNA1S |
More about : CACNA1S |
| Long gene name: |
calcium voltage-gated channel subunit alpha1 S |
| Synonyms gene: |
HOKPP MHS5 CACNL1A3 |
| Synonyms gene name: |
L type, alpha 1S subunit , calcium channel, voltage-dependent |
| Locus: |
1q32, 1 |
| Discovery year: |
1992-03-27 |
| GenBank acession: |
L33798 |
| Entrez gene record: |
779 |
| Pubmed identfication: |
7916735 16382099 |
| RefSeq identity: |
NM_000069 |
| Classification: |
Calcium voltage-gated channel subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000035784 |
| Locus Specific Databases: |
LOVD - Leiden Open Variation Database |