| Long name: |
Biotin Conjugated, UVRAG Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
UVRAG |
| Specificity: |
This is a highly specific antibody against UVRAG |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human UVRAG/DHTX |
| Gene ID number: |
7405 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Autophagy is the degradation of cellular proteins in the lysosomes, Mutations in the gene encoding UVRAG have been associated with colon cancer, UVRAG contains one C2 domain, UVRAG has been found to complement the ultraviolet sensitivity of xeroderma pigmentosum group C cells, UVRAG has been shown to activate the BECN1/PI 3-kinase complex, UVRAG is found at highest levels in kidney, Ubiquitously expressed, also known as p63 or DHTX, and when this pathway is suppressed, cell growth is deregulated, is a 699 amino acid cytoplasmic protein, liver and brain, lung, suggesting that UVRAG is also involved in suppressing the proliferation and tumorigenicity of human colon cancer cells, which is thought to be involved in calcium-dependent phospholipid binding, which promotes autophagy, UVRAG |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
VPS38 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
UVRAG Conjugated |
| Short name: |
Conjugated, UVRAG Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, UVRAG (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
12640 |
| Gene: |
UVRAG |
More about : UVRAG |
| Long gene name: |
UV radiation resistance associated |
| Synonyms gene name: |
UV radiation resistance associated gene |
| Synonyms name: |
beclin 1 binding protein |
| Locus: |
11q13, 5 |
| Discovery year: |
1997-01-10 |
| GenBank acession: |
X99050 AB012958 |
| Entrez gene record: |
7405 |
| Pubmed identfication: |
9169138 16799551 18843052 |
| RefSeq identity: |
NM_003369 |
| Classification: |
C2 domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000165319 |