| Long name: |
UVRAG Primary Polyclonal Antibody |
| Also known as: |
UVRAG PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
UVRAG |
| Specificity: |
This is a highly specific antibody against UVRAG |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human UVRAG/DHTX |
| Gene ID number: |
7405 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Autophagy is the degradation of cellular proteins in the lysosomes, Mutations in the gene encoding UVRAG have been associated with colon cancer, UVRAG contains one C2 domain, UVRAG has been found to complement the ultraviolet sensitivity of xeroderma pigmentosum group C cells, UVRAG has been shown to activate the BECN1/PI 3-kinase complex, UVRAG is found at highest levels in kidney, Ubiquitously expressed, also known as p63 or DHTX, and when this pathway is suppressed, cell growth is deregulated, is a 699 amino acid cytoplasmic protein, liver and brain, lung, suggesting that UVRAG is also involved in suppressing the proliferation and tumorigenicity of human colon cancer cells, which is thought to be involved in calcium-dependent phospholipid binding, which promotes autophagy, UVRAG |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Disrupted in heterotaxy, UV radiation resistance associated, UV radiation resistance associated gene, UV radiation resistance associated gene protein, UV radiation resistance-associated gene protein, UVRAG, UVRAG_HUMAN, p63, DHTX |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
UVRAG |
| Short name: |
UVRAG Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
UVRAG (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
12640 |
| Gene: |
UVRAG |
More about : UVRAG |
| Long gene name: |
UV radiation resistance associated |
| Synonyms gene name: |
UV radiation resistance associated gene |
| Synonyms: |
VPS38 |
| Synonyms name: |
beclin 1 binding protein |
| Locus: |
11q13, 5 |
| Discovery year: |
1997-01-10 |
| GenBank acession: |
X99050 AB012958 |
| Entrez gene record: |
7405 |
| Pubmed identfication: |
9169138 16799551 18843052 |
| RefSeq identity: |
NM_003369 |
| Classification: |
C2 domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000165319 |