| Long name: |
Cy3 Conjugated, CPN2 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
cy3 conjugation kit |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CPN2 |
| Specificity: |
This is a highly specific antibody against CPN2 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human CPN2 |
| Gene ID number: |
1370 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Because of the highly conserved active sites and the possible redundant functions of carboxypeptidases, By removing only one amino acid, CPN has the ability to change peptide activity and receptor binding, CPN is a member of a larger family of carboxypeptidases, CPN2, It consists of 2 identical 83 kDa regulatory subunits (CPN2) and 2 identical 50 kDa catalytic subunits (CPN1), It is a 280 kDa tetrameric glycoprotein that is synthesized by the liver and secreted into the plasma, Under some circumstances it may be an allosteric modifier of the catalytic subunit, and cleaves carboxy-terminal arginines and lysines from peptides found in the bloodstream such as complement anaphylatoxins, and creatine kinase MM (CK-MM), binds and stabilizes the catalytic subunit at 37 degrees Celsius and keeps it in circulation, it has been difficult to elucidate the role of CPN in disease processes, kinins, many of which also cleave arginine and lysine, the 83 kDa subunit, CPN2 is a zinc metalloprotease |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
512, 550nm/570, 615nm |
| Synonyms: |
CPN2 |
| Properties: |
1 of the CPN2 Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CPN2 Conjugated |
| Short name: |
Conjugated, CPN2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy3 |
| Alternative name: |
cyanine 3 coupled, CPN2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
2315 |
| Gene: |
CPNE2 |
More about : CPNE2 |
| Long gene name: |
copine 2 |
| Synonyms gene name: |
copine II |
| Locus: |
16q13 |
| Discovery year: |
1999-02-09 |
| Entrez gene record: |
221184 |
| Pubmed identfication: |
9430674 |
| RefSeq identity: |
NM_152727 |
| Classification: |
Copines |
| Havana BLAST/BLAT: |
OTTHUMG00000133471 |