| Catalog number: | bs-9907R-A555 |
|---|---|
| Price: | 373 € |
| Supplier: | abebio |
| Product name: | CPN2 Antibody, ALEXA FLUOR 555 |
| Quantity: | 1x plate of 48 wells |
| Related search: |
| Long name: | ALEXA FLUOR 555 Conjugated, CPN2 Polyclonal Antibody |
|---|---|
| Also known as: | Anti-CPN2 PAb ALEXA FLUOR 555 |
| Category: | Conjugated Primary Antibodies |
| Conjugated with: | 555, ALEXA FLUOR® |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | CPN2 |
| Specificity: | This is a highly specific antibody against CPN2 |
| Modification: | Unmodified |
| Modification Site: | None |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Source: | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CPN2 |
| Gene ID Number: | 1370 |
| Tested applications: | IF(IHC-P) |
| Recommended dilutions: | IF(IHC-P)(1:50-200) |
| Crossreactivity: | Mouse, Rat, Human |
| Cross-reactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: | Because of the highly conserved active sites and the possible redundant functions of carboxypeptidases, By removing only one amino acid, CPN has the ability to change peptide activity and receptor binding, CPN is a member of a larger family of carboxypeptidases, CPN2, It consists of 2 identical 83 kDa regulatory subunits (CPN2) and 2 identical 50 kDa catalytic subunits (CPN1), It is a 280 kDa tetrameric glycoprotein that is synthesized by the liver and secreted into the plasma, Under some circumstances it may be an allosteric modifier of the catalytic subunit, and cleaves carboxy-terminal arginines and lysines from peptides found in the bloodstream such as complement anaphylatoxins, and creatine kinase MM (CK-MM), binds and stabilizes the catalytic subunit at 37 degrees Celsius and keeps it in circulation, it has been difficult to elucidate the role of CPN in disease processes, kinins, many of which also cleave arginine and lysine, the 83 kDa subunit, CPN2 is a zinc metalloprotease |
| Purification: | Purified by Protein A |
| Storage conditions: | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: | 553nm/568nm |
| Synonyms: | CPN2 |
| Properties: | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: | ALEXA FLUOR 555, Alexa Fluor |
| Gene target: | CPN2 |
| Short name: | CPN2 Antibody |
| Technique: | antibodies against human proteins, antibodies for, Antibody |
| Label: | ALEXA FLUOR 555 |
| Alternative name: | ALEXA FLUOR 555, CPN2 (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 2315 |
| Gene: | CPNE2 | More about : CPNE2 |
| Long gene name: | copine 2 |
| Synonyms gene name: | copine II |
| Locus: | 16q13 |
| Discovery year: | 1999-02-09 |
| Entrez gene record: | 221184 |
| Pubmed identfication: | 9430674 |
| RefSeq identity: | NM_152727 |
| Classification: | Copines |
| Havana BLAST/BLAT: | OTTHUMG00000133471 |
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