| Catalog number: | bs-9847R-A350 |
|---|---|
| Price: | 332 € |
| Supplier: | Bioss Primary Conjugated Antibodies. |
| Product name: | AE2 Antibody, ALEXA FLUOR 350 |
| Quantity: | 100ul |
| Related search: |
| Long name: | ALEXA FLUOR 350 Conjugated, AE2 Polyclonal Antibody |
|---|---|
| Also known as: | Anti-AE2 PAb ALEXA FLUOR 350 |
| Category: | Conjugated Primary Antibodies |
| Conjugated with: | 350, ALEXA FLUOR® |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | AE2 |
| Specificity: | This is a highly specific antibody against AE2 |
| Modification: | Unmodified |
| Modification Site: | None |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Subcellular location: | Extracellular |
| Source: | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human AE2/SLC4A2 |
| Gene ID Number: | 6522 |
| Tested applications: | IF(IHC-P) |
| Recommended dilutions: | IF(IHC-P)(1:50-200) |
| Crossreactivity: | Human |
| Cross-reactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: | Bicarbonate is secreted from hepatocytes and cholangiocytes through parallel mechanisms, Gene silencing of AE2 causes a marked inhibition of unstimulated and secretin-stimulated chloride/bicarbonate exchange, The AE2 protein regulates pH, The excretion of bicarbonate at both the canaliculi and the bile ducts is an important contributor to the generation of bile-salt independent flow, cell volume and transepithelial ion transport in many tissues, chloride concentration, including hormones, innervation/neuropeptides and biliary constituents, which involve chloride efflux through activation of chloride channels and further bicarbonate secretion via AE2 (also designated SLC4A2)-mediated chloride/bicarbonate exchange, which maintains the bile acid pool that is crucial for secretin to induce bicarbonate-rich choleresis, Primary canalicular bile undergoes a process of fluidization and alkalinization along the biliary tract that is influenced by several factors |
| Purification: | Purified by Protein A |
| Storage conditions: | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: | 343nm/442nm |
| Synonyms: | AE2 |
| Properties: | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: | ALEXA FLUOR 350, Alexa Fluor |
| Gene target: | AE2 |
| Short name: | AE2 Antibody |
| Technique: | antibodies against human proteins, antibodies for, Antibody |
| Label: | ALEXA FLUOR 350 |
| Alternative name: | ALEXA FLUOR 350, AE2 (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 25076 |
| Gene: | NBPF3 | More about : NBPF3 |
| Long gene name: | neuroblastoma breakpoint family member 3 |
| Synonyms gene name: | member 3 , neuroblastoma breakpoint family |
| Locus: | 1p36, 12 |
| Discovery year: | 2005-11-23 |
| GenBank acession: | BC024011 |
| Entrez gene record: | 84224 |
| Pubmed identfication: | 11230166 16079250 |
| RefSeq identity: | NM_032264 |
| Classification: | Neuroblastoma breakpoint family |
| Havana BLAST/BLAT: | OTTHUMG00000002944 |
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