| Long name: |
FITC Conjugated, GDN Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
GDN |
| Specificity: |
This is a highly specific antibody against GDN |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human GDN/SERPINE2 |
| Gene ID number: |
5270 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
An imbalance between PN-1 and thrombin may be a contributing factor in the pathology of Alzheimerâ, It is involved in tissue remodeling, PN-1 expression is abundant in the nervous system, Protease nexin-1 (PN-1) is a serpin that inactivates several proteases, Serpins are secreted glycoproteins that contain a stretch of peptide that mimics a true substrate for a corresponding serine protease, cellular invasiveness, complement activation, including the control of blood coagulation, including thrombin, matrix degradation and tumor growth, plasminogen activators (PA) and plasmin, programmed cell death and development, thereby playing a role in neural injury and repair processes, urokinase, where it inhibits thrombin, &euro, &trade, The serine protease inhibitors (serpins) compose a superfamily of proteins with a diverse set of functions, s disease |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
PN1 GDN PNI nexin |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
GDN Conjugated |
| Short name: |
FITC Conjugated, GDN Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, GDN (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
8951 |
| Gene: |
SERPINE2 |
More about : SERPINE2 |
| Long gene name: |
serpin family E member 2 |
| Synonyms gene: |
PI7 |
| Synonyms gene name: |
clade E (nexin, clade E (nexin, member 2 , member 2 serpin peptidase inhibitor, plasminogen activator inhibitor type 1), plasminogen activator inhibitor type 1), serine (or cysteine) proteinase inhibitor |
| Synonyms name: |
glial-derived nexin 1 |
| Locus: |
2q36, 1 |
| Discovery year: |
1994-09-01 |
| GenBank acession: |
M17783 |
| Entrez gene record: |
5270 |
| Pubmed identfication: |
7665170 24172014 |
| RefSeq identity: |
NM_006216 |
| Classification: |
Serpin peptidase inhibitors |
| Havana BLAST/BLAT: |
OTTHUMG00000133163 |