| Long name: |
ALEXA FLUOR 647 Conjugated, GDN Polyclonal Antibody |
| Also known as: |
Anti-GDN PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
GDN |
| Specificity: |
This is a highly specific antibody against GDN |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GDN/SERPINE2 |
| Gene ID Number: |
5270 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
An imbalance between PN-1 and thrombin may be a contributing factor in the pathology of Alzheimerâ, It is involved in tissue remodeling, PN-1 expression is abundant in the nervous system, Protease nexin-1 (PN-1) is a serpin that inactivates several proteases, Serpins are secreted glycoproteins that contain a stretch of peptide that mimics a true substrate for a corresponding serine protease, cellular invasiveness, complement activation, including the control of blood coagulation, including thrombin, matrix degradation and tumor growth, plasminogen activators (PA) and plasmin, programmed cell death and development, thereby playing a role in neural injury and repair processes, urokinase, where it inhibits thrombin, &euro, &trade, The serine protease inhibitors (serpins) compose a superfamily of proteins with a diverse set of functions, s disease |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
PN1 GDN PNI nexin |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the GDN Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
GDN |
| Short name: |
GDN Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, GDN (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
8951 |
| Gene: |
SERPINE2 |
More about : SERPINE2 |
| Long gene name: |
serpin family E member 2 |
| Synonyms gene: |
PI7 |
| Synonyms gene name: |
clade E (nexin, clade E (nexin, member 2 , member 2 serpin peptidase inhibitor, plasminogen activator inhibitor type 1), plasminogen activator inhibitor type 1), serine (or cysteine) proteinase inhibitor |
| Synonyms name: |
glial-derived nexin 1 |
| Locus: |
2q36, 1 |
| Discovery year: |
1994-09-01 |
| GenBank acession: |
M17783 |
| Entrez gene record: |
5270 |
| Pubmed identfication: |
7665170 24172014 |
| RefSeq identity: |
NM_006216 |
| Classification: |
Serpin peptidase inhibitors |
| Havana BLAST/BLAT: |
OTTHUMG00000133163 |