| Long name: |
GDN Primary Polyclonal Antibody |
| Also known as: |
GDN PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
GDN |
| Specificity: |
This is a highly specific antibody against GDN |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GDN/SERPINE2 |
| Gene ID number: |
5270 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
An imbalance between PN-1 and thrombin may be a contributing factor in the pathology of Alzheimerâ, It is involved in tissue remodeling, PN-1 expression is abundant in the nervous system, Protease nexin-1 (PN-1) is a serpin that inactivates several proteases, Serpins are secreted glycoproteins that contain a stretch of peptide that mimics a true substrate for a corresponding serine protease, cellular invasiveness, complement activation, including the control of blood coagulation, including thrombin, matrix degradation and tumor growth, plasminogen activators (PA) and plasmin, programmed cell death and development, thereby playing a role in neural injury and repair processes, urokinase, where it inhibits thrombin, &euro, &trade, The serine protease inhibitors (serpins) compose a superfamily of proteins with a diverse set of functions, s disease |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
GDN, GDN_HUMAN, Glia-derived nexin, P17 antibody Peptidase inhibitor 7, PN-1, PN1, PNI, Pi-7, Plasminogen activator inhibitor type 1, Protease inhibitor 7, Protease nexin 1, Protease nexin I, SERPINE 2, Serpin E2, Serpin peptidase inhibitor, Serpine2, clade E nexin, member 2, member 2, plasminogen activator inhibitor type 1, Glia derived nexin |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
GDN |
| Short name: |
GDN Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
GDN (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
8951 |
| Gene: |
SERPINE2 |
More about : SERPINE2 |
| Long gene name: |
serpin family E member 2 |
| Synonyms gene: |
PI7 |
| Synonyms gene name: |
clade E (nexin, clade E (nexin, member 2 , member 2 serpin peptidase inhibitor, plasminogen activator inhibitor type 1), plasminogen activator inhibitor type 1), serine (or cysteine) proteinase inhibitor |
| Synonyms: |
PN1 GDN PNI nexin |
| Synonyms name: |
glial-derived nexin 1 |
| Locus: |
2q36, 1 |
| Discovery year: |
1994-09-01 |
| GenBank acession: |
M17783 |
| Entrez gene record: |
5270 |
| Pubmed identfication: |
7665170 24172014 |
| RefSeq identity: |
NM_006216 |
| Classification: |
Serpin peptidase inhibitors |
| Havana BLAST/BLAT: |
OTTHUMG00000133163 |