| Long name: |
ALEXA FLUOR 647 Conjugated, GPR71 Polyclonal Antibody |
| Also known as: |
Anti-GPR71 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
GPR71 |
| Specificity: |
This is a highly specific antibody against GPR71 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GPR71/T1R2 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
A controversial fifth taste, A family of G protein coupled receptors are involved in taste perception, Artificial sweeteners bind to either Gbg or Gaq coupled T1Rs to activate PLCb2 and generate IP3 and DAG, Both pathways ultimately lead to neurotransmitter release, First, Sweet taste transduction is carried out by two pathways (2), T1R1, T1R2, The T1R family consists of three members, The T1R1 and T1R3 heterodimer recognizes L-amino-acids to perceive umami taste, The T1R2 and T1R3 heterodimer functions as a receptor for sweet taste, The mouse T1R3 gene maps to chromosome 4 near the Sac locus, There are four widely accepted categories of taste perception, These proteins form heterodimers, a primary determinant of sweet preference in mice, and T1R3 (1-4), and T2R, and acesulfame-K (1â, and fungiform taste papillae, and includes T1R, and it is expressed in a subset of taste cells in circumvallate, and recognizes several sweet-tasting molecules, and sour, bitter, dulcin, foliate, has also been described, known as umami or monosodium glutamate (MSG), saccharin, salty, such as sucrose, sucrose and other sugars activate Gas via the T1Rs, sweet, which activates adenylyl cyclase to generate cAMP, which alters the selectivity of the subunits (1-4), which is involved in bitter taste perception, which is involved in sweet and umami taste perception, &euro, &ldquo, 4), The sense of taste provides animals with valuable information about the quality and nutritional value of food |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
T1R2 TR2 |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the GPR71 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
GPR71 |
| Short name: |
GPR71 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, GPR71 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
14905 |
| Gene: |
TAS1R2 |
More about : TAS1R2 |
| Long gene name: |
taste 1 receptor member 2 |
| Synonyms gene: |
GPR71 |
| Synonyms gene name: |
G protein-coupled receptor 71 taste receptor, member 2 , type 1 |
| Locus: |
1p36, 13 |
| Discovery year: |
2001-03-21 |
| Entrez gene record: |
80834 |
| Classification: |
Taste 1 receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000002442 |