| Long name: |
HRP Conjugated, p150 CAF1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
HRP Conjugated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
p150 CAF1 |
| Specificity: |
This is a highly specific antibody against p150 CAF1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human p150 CAF1 |
| Gene ID number: |
10036 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Also involved in vitamin D-coupled transcription regulation via its association with the WINAC complex, Assembles histone octamers onto replicating DNA in vitro, CAF-1 performs the first step of the nucleosome assembly process, CHAF1A binds to histones H3 and H4, It may play a role in heterochromatin maintenance in proliferating cells by bringing newly synthesized cbx proteins to heterochromatic DNA replication foci (By similarity), The CCR4-NOT complex functions as general transcription regulation complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), a complex thought to mediate chromatin assembly in DNA replication and DNA repair, bringing newly synthesized histones H3 and H4 to replicating DNA, histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer, which is required for the ligand-bound VDR-mediated transrepression of the CYP27B1 gene, Core component of the CAF-1 complex |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% Gentamicin, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Properties: |
Also monoclonal HRP conjugates are often used for Western Blot, HRP conjugates are often primary rabbit polyclonal antibodies couples to the , found in the roots of , (HRP), C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°, enzyme , horseradish, horseradish peroxidase |
| Gene target: |
p150 CAF1 Conjugated |
| Short name: |
Conjugated, p150 CAF1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
HRP |
| Alternative name: |
horseradish peroxidase coupled, p150 CAF1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
14101 |
| Gene: |
CNOT7 |
More about : CNOT7 |
| Long gene name: |
CCR4-NOT transcription complex subunit 7 |
| Synonyms gene: |
CAF1 |
| Synonyms gene name: |
CCR4-NOT transcription complex, subunit 7 |
| Synonyms name: |
BTG1 binding factor 1 |
| Locus: |
8p22 |
| Discovery year: |
2000-12-01 |
| GenBank acession: |
L46722 |
| Entrez gene record: |
29883 |
| Pubmed identfication: |
10637334 1538749 17264152 |
| RefSeq identity: |
NM_013354 |
| Classification: |
CCR4-NOT transcription complex |
| Havana BLAST/BLAT: |
OTTHUMG00000096971 |