| Long name: |
p150 CAF1 Primary Polyclonal Antibody |
| Also known as: |
p150 CAF1 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
p150 CAF1 |
| Specificity: |
This is a highly specific antibody against p150 CAF1 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human p150 CAF1 |
| Gene ID number: |
10036 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Also involved in vitamin D-coupled transcription regulation via its association with the WINAC complex, Assembles histone octamers onto replicating DNA in vitro, CAF-1 performs the first step of the nucleosome assembly process, CHAF1A binds to histones H3 and H4, It may play a role in heterochromatin maintenance in proliferating cells by bringing newly synthesized cbx proteins to heterochromatic DNA replication foci (By similarity), The CCR4-NOT complex functions as general transcription regulation complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), a complex thought to mediate chromatin assembly in DNA replication and DNA repair, bringing newly synthesized histones H3 and H4 to replicating DNA, histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer, which is required for the ligand-bound VDR-mediated transrepression of the CYP27B1 gene, Core component of the CAF-1 complex |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
CAF, CAF 1, CAF 1 150 kDa subunit, CAF 1 subunit A, CAF I 150 kDa subunit, CAF I p150, CAF Ip150, CAF-1 subunit A, CAF-I 150 kDa subunit, CAF-I p150, CAF1, CAF1 150 kDa subunit, CAF1 p150 Subunit, CAF1 subunit A, CAF1A, CAF1A, CAF1A_HUMAN, CAF1B, CAF1P150, CAF1P155, CAF1P155, CHAF1A, Chromatin Assembly Factor 1 Subunit A p150, Chromatin Assembly Factor I, Chromatin assembly factor 1 subunit A, Chromatin assembly factor I 150 kDa, Chromatin assembly factor I 150 kDa, Chromatin assembly factor I p150 subunit, DCAF1, NURF150, Nucleosome Remodeling Factor 150kDa Subunit, P150, hp150, CAF-1 p150 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
p150 CAF1 |
| Short name: |
p150 CAF1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
p150 CAF1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
14101 |
| Gene: |
CNOT7 |
More about : CNOT7 |
| Long gene name: |
CCR4-NOT transcription complex subunit 7 |
| Synonyms gene: |
CAF1 |
| Synonyms gene name: |
CCR4-NOT transcription complex, subunit 7 |
| Synonyms name: |
BTG1 binding factor 1 |
| Locus: |
8p22 |
| Discovery year: |
2000-12-01 |
| GenBank acession: |
L46722 |
| Entrez gene record: |
29883 |
| Pubmed identfication: |
10637334 1538749 17264152 |
| RefSeq identity: |
NM_013354 |
| Classification: |
CCR4-NOT transcription complex |
| Havana BLAST/BLAT: |
OTTHUMG00000096971 |