| Long name: |
FITC Conjugated, CNOT2 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CNOT2 |
| Specificity: |
This is a highly specific antibody against CNOT2 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human CNOT2 |
| Gene ID number: |
4848 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
CNOT1, CNOT2 belongs to the CNOT2/3/5 family and is part of the CCR4-NOT complex, CNOT2) are involved in influencing nuclear hormone receptor activities, Increased expression of the CNOT2 subunit acts to strongly repress transcription by RNA polymerase II, Repression by the NOT-Box is sensitive to treatment with the histone deacetylase (HDAC) inhibitor trichostatin A, The CCR4-NOT complex is also involved in the regulation of Histone H3 lysine 4 methylation through a ubiquitin-dependent pathway that likely involves the proteasome, The CCR4-NOT complex is an evolutionarily conserved, This repressive effect is mediated by a conserved NOT-Box, Various subunits (e, multi-component complex known to be involved in transcription as well as mRNA degradation, which is located at the C-terminus of CNOT2 proteins, CNOT2 (CCR4-NOT transcription complex subunit 2) is a ubiquitous protein encoded by the human gene CNOT2, g |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
CDC36 NOT2H |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CNOT2 Conjugated |
| Short name: |
FITC Conjugated, CNOT2 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, CNOT2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
7878 |
| Gene: |
CNOT2 |
More about : CNOT2 |
| Long gene name: |
CCR4-NOT transcription complex subunit 2 |
| Synonyms gene: |
NOT2 |
| Synonyms gene name: |
CCR4-NOT transcription complex, subunit 2 |
| Locus: |
12q15 |
| Discovery year: |
1996-07-19 |
| GenBank acession: |
AF180473 |
| Entrez gene record: |
4848 |
| Pubmed identfication: |
10637334 |
| Classification: |
CCR4-NOT transcription complex |
| Havana BLAST/BLAT: |
OTTHUMG00000169481 |