| Long name: |
ALEXA FLUOR 647 Conjugated, CNOT2 Polyclonal Antibody |
| Also known as: |
Anti-CNOT2 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CNOT2 |
| Specificity: |
This is a highly specific antibody against CNOT2 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CNOT2 |
| Gene ID Number: |
4848 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
CNOT1, CNOT2 belongs to the CNOT2/3/5 family and is part of the CCR4-NOT complex, CNOT2) are involved in influencing nuclear hormone receptor activities, Increased expression of the CNOT2 subunit acts to strongly repress transcription by RNA polymerase II, Repression by the NOT-Box is sensitive to treatment with the histone deacetylase (HDAC) inhibitor trichostatin A, The CCR4-NOT complex is also involved in the regulation of Histone H3 lysine 4 methylation through a ubiquitin-dependent pathway that likely involves the proteasome, The CCR4-NOT complex is an evolutionarily conserved, This repressive effect is mediated by a conserved NOT-Box, Various subunits (e, multi-component complex known to be involved in transcription as well as mRNA degradation, which is located at the C-terminus of CNOT2 proteins, CNOT2 (CCR4-NOT transcription complex subunit 2) is a ubiquitous protein encoded by the human gene CNOT2, g |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
CDC36 NOT2H |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the CNOT2 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
CNOT2 |
| Short name: |
CNOT2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, CNOT2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
7878 |
| Gene: |
CNOT2 |
More about : CNOT2 |
| Long gene name: |
CCR4-NOT transcription complex subunit 2 |
| Synonyms gene: |
NOT2 |
| Synonyms gene name: |
CCR4-NOT transcription complex, subunit 2 |
| Locus: |
12q15 |
| Discovery year: |
1996-07-19 |
| GenBank acession: |
AF180473 |
| Entrez gene record: |
4848 |
| Pubmed identfication: |
10637334 |
| Classification: |
CCR4-NOT transcription complex |
| Havana BLAST/BLAT: |
OTTHUMG00000169481 |