| Long name: |
CNOT2 Primary Polyclonal Antibody |
| Also known as: |
CNOT2 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
CNOT2 |
| Specificity: |
This is a highly specific antibody against CNOT2 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CNOT2 |
| Gene ID number: |
4848 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
CNOT1, CNOT2 belongs to the CNOT2/3/5 family and is part of the CCR4-NOT complex, CNOT2) are involved in influencing nuclear hormone receptor activities, Increased expression of the CNOT2 subunit acts to strongly repress transcription by RNA polymerase II, Repression by the NOT-Box is sensitive to treatment with the histone deacetylase (HDAC) inhibitor trichostatin A, The CCR4-NOT complex is also involved in the regulation of Histone H3 lysine 4 methylation through a ubiquitin-dependent pathway that likely involves the proteasome, The CCR4-NOT complex is an evolutionarily conserved, This repressive effect is mediated by a conserved NOT-Box, Various subunits (e, multi-component complex known to be involved in transcription as well as mRNA degradation, which is located at the C-terminus of CNOT2 proteins, CNOT2 (CCR4-NOT transcription complex subunit 2) is a ubiquitous protein encoded by the human gene CNOT2, g |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
CCR4 NOT transcription complex subunit 2, CCR4-NOT transcription complex subunit 2, CCR4-associated factor 2, CDC36, CNOT2, CNOT2_HUMAN, HSPC131, MSTP046, NOT2, NOT2 negative regulator of transcription 2 yeast homolog, NOT2H, Negative regulator of transcription 2, CCR4 associated factor 2 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CNOT2 |
| Short name: |
CNOT2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
CNOT2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
7878 |
| Gene: |
CNOT2 |
More about : CNOT2 |
| Long gene name: |
CCR4-NOT transcription complex subunit 2 |
| Synonyms gene: |
NOT2 |
| Synonyms gene name: |
CCR4-NOT transcription complex, subunit 2 |
| Synonyms: |
CDC36 NOT2H |
| Locus: |
12q15 |
| Discovery year: |
1996-07-19 |
| GenBank acession: |
AF180473 |
| Entrez gene record: |
4848 |
| Pubmed identfication: |
10637334 |
| Classification: |
CCR4-NOT transcription complex |
| Havana BLAST/BLAT: |
OTTHUMG00000169481 |