| Long name: |
MARCH2 Primary Polyclonal Antibody |
| Also known as: |
MARCH2 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
37316 |
| Specificity: |
This is a highly specific antibody against 37316 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MARCH2 |
| Gene ID number: |
51257 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Expressed in a variety of tissues, MARCH2 (membrane-associated ring finger (C3HC4) 2), MARCH2 functions as an E3 ubiquitin-protein ligase that is thought to mediate the ubiquitination and subsequent degradation of CD71 and B7-2 and may be involved in endosomal protein trafficking, The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), also known as RNF172 or HSPC240, is a 246 amino acid multi-pass membrane protein that localizes to the endoplasmic reticulum and contains one RING-CH-type zinc finger, the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s), Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
E3 ubiquitin-protein ligase MARCH2, EC 6, MARCH II, MARCH-II, MARH2_HUMAN antibody Membrane associated RING CH protein II, Membrane associated RING finger protein 2, Membrane associated ring finger C3HC4 2, Membrane-associated RING finger protein 2, Membrane-associated RING-CH protein II, RING finger protein 172, RNF172, march2, - antibody HSPC240, 2, 3, E3 ubiquitin protein ligase MARCH2 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
MARCH2 |
| Short name: |
MARCH2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
E3 ubiquitin protein ligase (Antibody to), membrane-associated ring finger (C3HC4) 2 |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
E3 ubiquitin protein ligase, MARCH2 and IDBG-24762 and ENSG00000099785 and 51257, MARCH2 and IDBG-643827 and ENSBTAG00000021036 and 508949, March2 and IDBG-251885 and ENSMUSG00000079557 and 224703, Plasma membranes, metal ion binding, this GO :0004842 and ubiquitin-protein transferase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005765 and lysosomal membrane and cellular component this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005789 and endoplasmic reticulum membrane and cellular component this GO :0006897 and endocytosis and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0010008 and endosome membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016567 and protein ubiquitination and biological process this GO :0016874 and ligase activity and molecular function this GO :0031410 and cytoplasmic vesicle and cellular component this GO :0046872 and metal ion binding and molecular function, this GO :0004842 : ubiquitin-protein transferase activity, this GO :0004842 : ubiquitin-protein transferase activity and also this GO :0005515 : protein binding and also this GO :0008270 : zinc ion binding and also this GO :0016874 : ligase activity and also this GO :0046872 : metal ion binding, this GO :0005515 : protein binding, this GO :0008270 : zinc ion binding, this GO :0016874 : ligase activity, this GO :0046872 : metal ion binding, membrane-associated ring finger (C3HC4) 2 |
| Identity: |
28038 |
| Gene: |
MARCH2 |
More about : MARCH2 |
| Long gene name: |
membrane associated ring-CH-type finger 2 |
| Synonyms gene name: |
E3 ubiquitin protein ligase , membrane-associated ring finger (C3HC4) 2 membrane-associated ring finger (C3HC4) 2 |
| Synonyms: |
HSPC240 MARCH-II RNF172 |
| Locus: |
19p13, 2 |
| Discovery year: |
2005-01-26 |
| GenBank acession: |
AF151074 |
| Entrez gene record: |
51257 |
| Pubmed identfication: |
11042152 14722266 |
| RefSeq identity: |
NM_016496 |
| Classification: |
Membrane associated ring-CH-type fingers Ring finger proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000182282 |