| Long name: |
ALEXA FLUOR 488 Conjugated, RNF180 Polyclonal Antibody |
| Also known as: |
Anti-RNF180 PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
RNF180 |
| Specificity: |
This is a highly specific antibody against RNF180 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human RNF180 |
| Gene ID Number: |
285671 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, Expressed as three alternatively spliced isoforms, Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation, RNF180 (ring finger protein 180), RNF180 is an E3 ubiquitin ligase involved in the ubiquitin-proteasome pathway, RNF180 is encoded by a gene located on human chromosome 5, RNF180 is expressed in brain, RNF180 is well conserved among vertebrates, also known as Rines, is a 592 single-pass membrane protein that contains a single RING-type zinc finger, is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome, kidney, or of chromosome 5 altogether, testis and uterus and localizes to the endoplasmic reticulum, which contains 181 million base pairs and comprises nearly 6% of the human genome, while deletion of the q arm, The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the RNF180 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
RNF180 |
| Short name: |
RNF180 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, RNF180 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
27752 |
| Gene: |
RNF180 |
More about : RNF180 |
| Long gene name: |
ring finger protein 180 |
| Locus: |
5q12, 3 |
| Discovery year: |
2005-01-26 |
| GenBank acession: |
AK090756 |
| Entrez gene record: |
285671 |
| RefSeq identity: |
NM_178532 |
| Classification: |
Ring finger proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000162278 |