| Long name: |
Biotin Conjugated, SIP1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
SIP1 |
| Specificity: |
This is a highly specific antibody against SIP1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Nucleus |
| Source: |
KLH conjugated synthetic peptide derived from human SIP1 |
| Gene ID number: |
9839 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Mutations in the SIP1 gene cause a form of Hirschsprung disease (HSCR), Patients with SIP1 mutations show mental retardation, SIP1, SIP1, SIP1 contains a SMAD-binding domain, SIP1 plays a crucial role in normal embryonic development of neural structures and the neural crest, The human SIP1 gene maps to chromosome 2q22, ZFHX1B and ZEB2 (zinc finger E-box-binding protein 2), a homeodomain and two clusters of zinc fingers on the N- and C-termini, also known as SMADIP1, can be induced by TGFâ, delayed motor development, distinct facial features and/or congenital heart diseaseâ, epilepsy, for SMAD interacting protein 1, is a member of the delta-EF1/Zfh1 family of 2-handed zinc finger/homeodomain proteins, microcephaly, treatment, &circ, &euro, «, &rdquo, SMAD regulates gene expression by interacting with different classes of transcription factors including DNA-binding multi-zinc finger proteins, all symptoms of HSCR |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
SIP1 Conjugated |
| Short name: |
Conjugated, SIP1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, SIP1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
10884 |
| Gene: |
GEMIN2 |
More about : GEMIN2 |
| Long gene name: |
gem nuclear organelle associated protein 2 |
| Synonyms gene: |
SIP1 |
| Synonyms gene name: |
survival of motor neuron protein interacting protein 1 gem (nuclear organelle) associated protein 2 |
| Locus: |
14q21, 1 |
| Discovery year: |
1998-10-16 |
| GenBank acession: |
AF027150 |
| Entrez gene record: |
8487 |
| Pubmed identfication: |
9323130 9323129 11121410 |
| Classification: |
Gemins |
| Havana BLAST/BLAT: |
OTTHUMG00000028816 |