| Long name: |
ALEXA FLUOR 488 Conjugated, SIP1 Polyclonal Antibody |
| Also known as: |
Anti-SIP1 PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
SIP1 |
| Specificity: |
This is a highly specific antibody against SIP1 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Nucleus |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SIP1 |
| Gene ID Number: |
9839 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Mutations in the SIP1 gene cause a form of Hirschsprung disease (HSCR), Patients with SIP1 mutations show mental retardation, SIP1, SIP1, SIP1 contains a SMAD-binding domain, SIP1 plays a crucial role in normal embryonic development of neural structures and the neural crest, The human SIP1 gene maps to chromosome 2q22, ZFHX1B and ZEB2 (zinc finger E-box-binding protein 2), a homeodomain and two clusters of zinc fingers on the N- and C-termini, also known as SMADIP1, can be induced by TGFâ, delayed motor development, distinct facial features and/or congenital heart diseaseâ, epilepsy, for SMAD interacting protein 1, is a member of the delta-EF1/Zfh1 family of 2-handed zinc finger/homeodomain proteins, microcephaly, treatment, &circ, &euro, «, &rdquo, SMAD regulates gene expression by interacting with different classes of transcription factors including DNA-binding multi-zinc finger proteins, all symptoms of HSCR |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the SIP1 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
SIP1 |
| Short name: |
SIP1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, SIP1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
10884 |
| Gene: |
GEMIN2 |
More about : GEMIN2 |
| Long gene name: |
gem nuclear organelle associated protein 2 |
| Synonyms gene: |
SIP1 |
| Synonyms gene name: |
survival of motor neuron protein interacting protein 1 gem (nuclear organelle) associated protein 2 |
| Locus: |
14q21, 1 |
| Discovery year: |
1998-10-16 |
| GenBank acession: |
AF027150 |
| Entrez gene record: |
8487 |
| Pubmed identfication: |
9323130 9323129 11121410 |
| Classification: |
Gemins |
| Havana BLAST/BLAT: |
OTTHUMG00000028816 |