| Long name: |
Biotin Conjugated, RNF92 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
RNF92 |
| Specificity: |
This is a highly specific antibody against RNF92 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human TRIM11/RNF92 |
| Gene ID number: |
81559 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Antiviral activity depends on a functional E3 ubiquitin-protein ligase domain, May also inhibit PAX6 transcriptional activity, May contribute to the innate restriction of retroviruses, May contribute to the regulation of the intracellular level of HN (humanin) or HN-containing proteins through the proteasomal degradation pathway, May regulate TRIM5 turnover via the proteasome pathway, Mediates MED15 ubiquitination leading to proteasomal degradation, Mediates PAX6 ubiquitination leading to proteasomal degradation, Upon overexpression, by suppressing viral gene expression, including insoluble PAX6, poly-Gln repeat expanded HTT and poly-Ala repeat expanded ARX, possibly in part by preventing the binding of PAX6 to its consensus sequences, reduces HIV-1 and murine leukemia virus infectivity, thereby modulating cortical neurogenesis, thus counteracting the TRIM5-mediated cross-species restriction of retroviral infection at early stages of the retroviral life cycle, E3 ubiquitin-protein ligase that promotes the degradation of insoluble ubiquitinated proteins |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
RNF92 BIA1 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
RNF92 Conjugated |
| Short name: |
Conjugated, RNF92 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, RNF92 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
16281 |
| Gene: |
TRIM11 |
More about : TRIM11 |
| Long gene name: |
tripartite motif containing 11 |
| Synonyms gene name: |
tripartite motif-containing 11 |
| Locus: |
1q42, 13 |
| Discovery year: |
2001-08-07 |
| GenBank acession: |
AF220125 |
| Entrez gene record: |
81559 |
| Pubmed identfication: |
11331580 |
| RefSeq identity: |
NM_145214 |
| Classification: |
Tripartite motif containing Ring finger proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000039773 |