| Long name: |
RNF92 Primary Polyclonal Antibody |
| Also known as: |
RNF92 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
RNF92 |
| Specificity: |
This is a highly specific antibody against RNF92 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TRIM11/RNF92 |
| Gene ID number: |
81559 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Antiviral activity depends on a functional E3 ubiquitin-protein ligase domain, May also inhibit PAX6 transcriptional activity, May contribute to the innate restriction of retroviruses, May contribute to the regulation of the intracellular level of HN (humanin) or HN-containing proteins through the proteasomal degradation pathway, May regulate TRIM5 turnover via the proteasome pathway, Mediates MED15 ubiquitination leading to proteasomal degradation, Mediates PAX6 ubiquitination leading to proteasomal degradation, Upon overexpression, by suppressing viral gene expression, including insoluble PAX6, poly-Gln repeat expanded HTT and poly-Ala repeat expanded ARX, possibly in part by preventing the binding of PAX6 to its consensus sequences, reduces HIV-1 and murine leukemia virus infectivity, thereby modulating cortical neurogenesis, thus counteracting the TRIM5-mediated cross-species restriction of retroviral infection at early stages of the retroviral life cycle, E3 ubiquitin-protein ligase that promotes the degradation of insoluble ubiquitinated proteins |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
E3 ubiquitin protein ligase TRIM11, E3 ubiquitin-protein ligase TRIM11, Protein BIA1, RING finger protein 92, RNF 92, TRI11_HUMAN, TRIM11, Trim 11, Tripartite mot containing 11, Tripartite mot-containing protein 11, tripartite mot protein 11, BIA 1 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
RNF92 |
| Short name: |
RNF92 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
RNF92 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
16281 |
| Gene: |
TRIM11 |
More about : TRIM11 |
| Long gene name: |
tripartite motif containing 11 |
| Synonyms gene name: |
tripartite motif-containing 11 |
| Synonyms: |
RNF92 BIA1 |
| Locus: |
1q42, 13 |
| Discovery year: |
2001-08-07 |
| GenBank acession: |
AF220125 |
| Entrez gene record: |
81559 |
| Pubmed identfication: |
11331580 |
| RefSeq identity: |
NM_145214 |
| Classification: |
Tripartite motif containing Ring finger proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000039773 |