| Long name: |
FITC Conjugated, Tankyrase Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Tankyrase |
| Specificity: |
This is a highly specific antibody against Tankyrase |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
1140-1171/1327 |
| Source: |
KLH conjugated synthetic peptide derived from human Tankyrase |
| Gene ID number: |
8658 |
| Swiss Prot: |
O95271 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
2 key components of the beta-catenin destruction complex: poly-ADP-ribosylated target proteins are recognized by RNF146, Acts as an activator of the Wnt signaling pathway by mediating poly-ADP-ribosylation (PARsylation) of AXIN1 and AXIN2, Also mediates PARsylation of BLZF1 and CASC3, Involved in centrosome maturation during prometaphase by mediating PARsylation of HEPACAM2/MIKI, May also regulate vesicle trafficking and modulate the subcellular distribution of SLC2A4/GLUT4-vesicles, May be involved in spindle pole assembly through PARsylation of NUMA1, Mediates PARsylation of TERF1, Stimulates 26S proteasome activity, followed by recruitment of RNF146 and subsequent ubiquitination, telomere length and vesicle trafficking, thereby contributing to the regulation of telomere length, which mediates their ubiquitination and subsequent degradation, Poly-ADP-ribosyltransferase involved in various processes such as Wnt signaling pathway |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
ADP-ribosyltransferase diphtheria toxin-like 5, ARTD5, PARP-5a, PARP5A, PARPL, Poly [ADP-ribose] polymerase 5A, TANK1, TINF1, TNKS, TNKS-1, TNKS1, TRF1-interacting ankyrin-related ADP-ribose polymerase, Tankyrase I, Tankyrase-1, pART5, TIN1 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Tankyrase Conjugated |
| Short name: |
FITC Conjugated, Tankyrase Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, Tankyrase (Antibody to) |
| Alternative technique: |
antibodies |