| Long name: |
Cy7 Conjugated, Tankyrase Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Cy7 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Tankyrase |
| Specificity: |
This is a highly specific antibody against Tankyrase |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
1140-1171/1327 |
| Source: |
KLH conjugated synthetic peptide derived from human Tankyrase |
| Gene ID number: |
8658 |
| Swiss Prot: |
O95271 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
2 key components of the beta-catenin destruction complex: poly-ADP-ribosylated target proteins are recognized by RNF146, Acts as an activator of the Wnt signaling pathway by mediating poly-ADP-ribosylation (PARsylation) of AXIN1 and AXIN2, Also mediates PARsylation of BLZF1 and CASC3, Involved in centrosome maturation during prometaphase by mediating PARsylation of HEPACAM2/MIKI, May also regulate vesicle trafficking and modulate the subcellular distribution of SLC2A4/GLUT4-vesicles, May be involved in spindle pole assembly through PARsylation of NUMA1, Mediates PARsylation of TERF1, Stimulates 26S proteasome activity, followed by recruitment of RNF146 and subsequent ubiquitination, telomere length and vesicle trafficking, thereby contributing to the regulation of telomere length, which mediates their ubiquitination and subsequent degradation, Poly-ADP-ribosyltransferase involved in various processes such as Wnt signaling pathway |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
743nm/767nm |
| Synonyms: |
ADP-ribosyltransferase diphtheria toxin-like 5, ARTD5, PARP-5a, PARP5A, PARPL, Poly [ADP-ribose] polymerase 5A, TANK1, TINF1, TNKS, TNKS-1, TNKS1, TRF1-interacting ankyrin-related ADP-ribose polymerase, Tankyrase I, Tankyrase-1, pART5, TIN1 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: |
These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths |
| Gene target: |
Tankyrase Conjugated |
| Short name: |
Conjugated, Tankyrase Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy7 |
| Alternative name: |
cyanine 7 coupled, Tankyrase (Antibody to) |
| Alternative technique: |
antibodies |