| Long name: |
ALEXA FLUOR 350 Conjugated, Tankyrase Polyclonal Antibody |
| Also known as: |
Anti-Tankyrase PAb ALEXA FLUOR 350 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
350, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Tankyrase |
| Specificity: |
This is a highly specific antibody against Tankyrase |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
1140-1171/1327 |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Tankyrase |
| Gene ID Number: |
8658 |
| Swiss Prot: |
O95271 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
2 key components of the beta-catenin destruction complex: poly-ADP-ribosylated target proteins are recognized by RNF146, Acts as an activator of the Wnt signaling pathway by mediating poly-ADP-ribosylation (PARsylation) of AXIN1 and AXIN2, Also mediates PARsylation of BLZF1 and CASC3, Involved in centrosome maturation during prometaphase by mediating PARsylation of HEPACAM2/MIKI, May also regulate vesicle trafficking and modulate the subcellular distribution of SLC2A4/GLUT4-vesicles, May be involved in spindle pole assembly through PARsylation of NUMA1, Mediates PARsylation of TERF1, Stimulates 26S proteasome activity, followed by recruitment of RNF146 and subsequent ubiquitination, telomere length and vesicle trafficking, thereby contributing to the regulation of telomere length, which mediates their ubiquitination and subsequent degradation, Poly-ADP-ribosyltransferase involved in various processes such as Wnt signaling pathway |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
343nm/442nm |
| Synonyms: |
TAB182 KIAA1741 FLJ45975 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 350, Alexa Fluor |
| Gene target: |
Tankyrase |
| Short name: |
Tankyrase Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 350 |
| Alternative name: |
ALEXA FLUOR 350, Tankyrase (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
19081 |
| Gene: |
TNKS1BP1 |
More about : TNKS1BP1 |
| Long gene name: |
tankyrase 1 binding protein 1 |
| Synonyms gene name: |
182kDa , tankyrase 1 binding protein 1 |
| Locus: |
11q12, 1 |
| Discovery year: |
2002-08-06 |
| GenBank acession: |
AB051528 |
| Entrez gene record: |
85456 |
| Pubmed identfication: |
11854288 |
| RefSeq identity: |
NM_033396 |
| Havana BLAST/BLAT: |
OTTHUMG00000167022 |