| Long name: |
ALEXA FLUOR 594 Conjugated, RNF75 Polyclonal Antibody |
| Also known as: |
Anti-RNF75 PAb ALEXA FLUOR 594 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
RNF75 |
| Specificity: |
This is a highly specific antibody against RNF75 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ROC1/RNF75 |
| Gene ID Number: |
9978 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
As a component of the CSA complex promotes the ubiquitination of ERCC6 resulting in proteasomal degradation, CUL2, CUL4 and CUL4 via its interaction with UBE2M, May be required for histone H3 and histone H4 ubiquitination in response to ultraviolet and for subsequent DNA repair, Probably also stimulates CDC34 autoubiquitination, Promotes the neddylation of CUL1, The functional specificity of the E3 ubiquitin-protein ligase complexes depends on the variable substrate recognition components, Through the RING-type zinc finger, including proteins involved in cell cycle progression, like CDC34, seems to recruit the E2 ubiquitination enzyme, signal transduction, to the complex and brings it into close proximity to the substrate, transcription and transcription-coupled nucleotide excision repair, E3 ubiquitin ligase component of multiple cullin-RING-based E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
ROC1 RNF75 BA554C12, 1 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated: |
Alexa conjugate 1 |
| Gene target: |
RNF75 |
| Short name: |
RNF75 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 594 |
| Alternative name: |
ALEXA FLUOR 594, RNF75 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
9928 |
| Gene: |
RBX1 |
More about : RBX1 |
| Long gene name: |
ring-box 1 |
| Synonyms gene name: |
E3 ubiquitin protein ligase , ring-box 1 ring-box 1 |
| Synonyms name: |
regulator of cullins 1 |
| Locus: |
22q13, 2 |
| Discovery year: |
1999-10-29 |
| GenBank acession: |
AF140598 |
| Entrez gene record: |
9978 |
| Pubmed identfication: |
10213691 10230407 |
| RefSeq identity: |
NM_014248 |
| Classification: |
Ring finger proteins SCF complex |
| Havana BLAST/BLAT: |
OTTHUMG00000151298 |