| Long name: |
HRP Conjugated, NIPA Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
HRP Conjugated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
NIPA |
| Specificity: |
This is a highly specific antibody against NIPA |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human NIPA |
| Gene ID number: |
51530 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Assembly of this SCF complex is regulated by cell-cycle-dependent phosphorylation of NIPA, Inactivation of NIPA by RNAi results in nuclear accumulation of cyclin B1 in interphase, NIPA (nuclear interaction partner of ALK) is a human F-box-containing protein that defines an SCF-type E3 ligase (SCFNIPA) controlling mitotic entry, Nuclear cyclin B1 is a substrate of SCFNIPA, SCFNIPA-based ubiquitination may regulate S-phase completion and mitotic entry in the mammalian cell cycle, The SCF class of E3 ubiquitin ligases is involved in this process by targeting cell cycle regulatory proteins for degradation by the proteasome, Thus, activation of cyclin B1-Cdk1 kinase activity, and premature mitotic entry, which restricts substrate ubiquitination activity to interphase, with the F-box subunit of the SCF specifically recruiting a given substrate to the SCF core, The regulated oscillation of protein expression is an essential mechanism of cell cycle control |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% Gentamicin, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
NIPA |
| Properties: |
Also monoclonal HRP conjugates are often used for Western Blot, HRP conjugates are often primary rabbit polyclonal antibodies couples to the , found in the roots of , (HRP), C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°, enzyme , horseradish, horseradish peroxidase |
| Gene target: |
NIPA Conjugated |
| Short name: |
Conjugated, NIPA Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
HRP |
| Alternative name: |
horseradish peroxidase coupled, NIPA (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
29913 |
| Gene: |
ZC3HC1 |
More about : ZC3HC1 |
| Long gene name: |
zinc finger C3HC-type containing 1 |
| Synonyms name: |
nuclear interaction partner of ALK |
| Locus: |
7q32, 2 |
| Discovery year: |
2004-11-19 |
| GenBank acession: |
AF151050 |
| Entrez gene record: |
51530 |
| Pubmed identfication: |
11042152 |
| RefSeq identity: |
NM_016478 |
| Classification: |
Zinc fingers |
| Havana BLAST/BLAT: |
OTTHUMG00000157648 |