| Long name: |
Ube2L3 Primary Polyclonal Antibody |
| Also known as: |
Ube2L3 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Ube2L3 |
| Specificity: |
This is a highly specific antibody against Ube2L3 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Ube2L3 |
| Gene ID number: |
7332 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
NF-kB maturation, Specifically, The Ub chain is then conjugated to the Ub-conjugating enzyme (E2) to generate an intermediate Ub-E2 complex, The Ub-ligase (E3) then catalyzes the transfer of Ub from E2 to the appropriate protein substrate, The first step requires the ATP-dependent activation of the Ub C-terminus and the assembly of multi-Ub chains by the Ub-activating enzyme known as the E1 component, UBE2E1 and UBE2L3, UBE2E1 interacts with the tumor suppressor protein TSSC5, UBE2L3 has been shown to mediate c-fos degradation, also designated UBCH6 and UBCH7 respectively in human, are E2 conjugating enzymes that interact with various proteins, human papilloma virus-mediated p53 and Myc protein degradation, The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
E2-F1, L UBC, L-UBC, UB2L3_HUMAN, UBCE7, UbcH7, UbcM4, Ube2l3, Ubiquitin carrier protein L3, Ubiquitin conjugating enzyme E2 L3, Ubiquitin protein ligase L3, Ubiquitin-conjugating enzyme E2 L3, Ubiquitin-conjugating enzyme E2-F1, Ubiquitin-protein ligase L3, E2 F1 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Ube2L3 |
| Short name: |
Ube2L3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Ube2L3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
12488 |
| Gene: |
UBE2L3 |
More about : UBE2L3 |
| Long gene name: |
ubiquitin conjugating enzyme E2 L3 |
| Synonyms gene name: |
ubiquitin-conjugating enzyme E2L 3 |
| Synonyms: |
UBCH7 |
| Locus: |
22q11, 21 |
| Discovery year: |
1997-03-21 |
| GenBank acession: |
AJ000519 |
| Entrez gene record: |
7332 |
| Pubmed identfication: |
8672131 9693040 |
| RefSeq identity: |
NM_198157 |
| Classification: |
Ubiquitin conjugating enzymes E2 |
| Havana BLAST/BLAT: |
OTTHUMG00000150823 |