| Catalog number: | bs-8334R-FITC |
|---|---|
| Price: | 856 € |
| Supplier: | accurate-monoclonals |
| Product name: | NIMP Antibody, FITC Conjugated |
| Quantity: | 1000ul |
| Related search: |
| Long name: | FITC Conjugated, NIMP Polyclonal Antibody |
|---|---|
| Category: | Conjugated Primary Antibodies |
| Conjugation: | Anti-FITC Antibody |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | NIMP |
| Specificity: | This is a highly specific antibody against NIMP |
| Modification: | Unmodified |
| Modification site: | None |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Source: | KLH conjugated synthetic peptide derived from human NIMP/RTN4IP1 |
| Gene ID number: | 84816 |
| Tested applications: | IF(IHC-P) |
| Recommended dilutions: | IF(IHC-P)(1:50-200) |
| Crossreactivity: | Mouse, Rat, Human |
| Crossreactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: | -B and -C, NIMP (NOGO-interacting mitochondrial protein), NIMP is expressed in mitochondrial-rich tissue such as kidney, Nogo exists in three different splice forms, Nogo is expressed by oligodendrocytes but not by Schwann cells, Nogo-A, There are three isoforms of NIMP that are produced as a result of alternative splicing events, Through interaction with Nogo, also known as RTN4IP1 (Reticulon-4-interacting protein 1), and associates primarily with the endoplasmic reticulum, and inhibits the spreading of 3T3 fibroblasts, heart, induces collapse of growth cones of chick dorsal root ganglion cells, is a 396 amino acid mitochondrial protein that contains a C-terminal oxidoreductaselike domain and numerous sites for phosphorylation, it is likely that NIMP plays a role in Nogo-induced inhibition of neurite growth, skeletal muscle and specific regions within the nervous system, Appears to be a potent inhibitor of regeneration following spinal cord injury, Nogo is an oligodendrocyte-specific member of the Reticulon family and is a component of CNS white matter that inhibits axon outgrowth |
| Purification method: | This antibody was purified via Protein A |
| Storage conditions: | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: | 494nm/518nm |
| Synonyms: | NIMP |
| Properties: | Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: | NIMP Conjugated |
| Short name: | FITC Conjugated, NIMP Antibody |
| Technique: | Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: | FITC |
| Alternative name: | fluorecein coupled, NIMP (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 18647 |
| Gene: | RTN4IP1 | More about : RTN4IP1 |
| Long gene name: | reticulon 4 interacting protein 1 |
| Locus: | 6q21 |
| Discovery year: | 2002-05-23 |
| GenBank acession: | AF336861 |
| Entrez gene record: | 84816 |
| Havana BLAST/BLAT: | OTTHUMG00000015304 |
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