| Catalog number: | bs-8334R |
|---|---|
| Price: | 602 € |
| Supplier: | genways |
| Product name: | NIMP Antibody |
| Quantity: | 1 vial |
| Related search: |
| Long name: | NIMP Primary Polyclonal Antibody |
|---|---|
| Also known as: | NIMP PAb |
| Category: | Primary Antibodies |
| Conjugation: | Unconjugated |
| Target Antigen: | NIMP |
| Specificity: | This is a highly specific antibody against NIMP |
| Modification(s): | None |
| Modification site(s): | Unmodified antibody |
| Clonality: | Polyclonal antibody |
| Clone number: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Source: | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human NIMP/RTN4IP1 |
| Gene ID number: | 84816 |
| Tested Applications: | IF(IHC-P), IHC-P, WB |
| Recommended dilutions: | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: | Mouse, Rat, Human |
| Cross reactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: | -B and -C, NIMP (NOGO-interacting mitochondrial protein), NIMP is expressed in mitochondrial-rich tissue such as kidney, Nogo exists in three different splice forms, Nogo is expressed by oligodendrocytes but not by Schwann cells, Nogo-A, There are three isoforms of NIMP that are produced as a result of alternative splicing events, Through interaction with Nogo, also known as RTN4IP1 (Reticulon-4-interacting protein 1), and associates primarily with the endoplasmic reticulum, and inhibits the spreading of 3T3 fibroblasts, heart, induces collapse of growth cones of chick dorsal root ganglion cells, is a 396 amino acid mitochondrial protein that contains a C-terminal oxidoreductaselike domain and numerous sites for phosphorylation, it is likely that NIMP plays a role in Nogo-induced inhibition of neurite growth, skeletal muscle and specific regions within the nervous system, Appears to be a potent inhibitor of regeneration following spinal cord injury, Nogo is an oligodendrocyte-specific member of the Reticulon family and is a component of CNS white matter that inhibits axon outgrowth |
| Purification method: | This antibody was purified via Protein A |
| Storage conditions: | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: | NIMP, NIMP/RTN4IP1, NOGO interacting mitochondrial protein, NOGO-interacting mitochondrial protein, RT4I1_HUMAN, Reticulon 4 interacting protein 1, Reticulon 4 interacting protein 1, Reticulon-4-interacting protein 1, Rtn4ip1, mitochondrial, mitochondrial |
| Properties: | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: | NIMP |
| Short name: | NIMP Antibody |
| Technique: | antibodies against human proteins, antibodies for, Antibody |
| Alternative name: | NIMP (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 18647 |
| Gene: | RTN4IP1 | More about : RTN4IP1 |
| Long gene name: | reticulon 4 interacting protein 1 |
| Synonyms: | NIMP |
| Locus: | 6q21 |
| Discovery year: | 2002-05-23 |
| GenBank acession: | AF336861 |
| Entrez gene record: | 84816 |
| Havana BLAST/BLAT: | OTTHUMG00000015304 |
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