| Long name: |
Biotin Conjugated, NIMP Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
NIMP |
| Specificity: |
This is a highly specific antibody against NIMP |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human NIMP/RTN4IP1 |
| Gene ID number: |
84816 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
-B and -C, NIMP (NOGO-interacting mitochondrial protein), NIMP is expressed in mitochondrial-rich tissue such as kidney, Nogo exists in three different splice forms, Nogo is expressed by oligodendrocytes but not by Schwann cells, Nogo-A, There are three isoforms of NIMP that are produced as a result of alternative splicing events, Through interaction with Nogo, also known as RTN4IP1 (Reticulon-4-interacting protein 1), and associates primarily with the endoplasmic reticulum, and inhibits the spreading of 3T3 fibroblasts, heart, induces collapse of growth cones of chick dorsal root ganglion cells, is a 396 amino acid mitochondrial protein that contains a C-terminal oxidoreductaselike domain and numerous sites for phosphorylation, it is likely that NIMP plays a role in Nogo-induced inhibition of neurite growth, skeletal muscle and specific regions within the nervous system, Appears to be a potent inhibitor of regeneration following spinal cord injury, Nogo is an oligodendrocyte-specific member of the Reticulon family and is a component of CNS white matter that inhibits axon outgrowth |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
NIMP |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
NIMP Conjugated |
| Short name: |
Conjugated, NIMP Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, NIMP (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
18647 |
| Gene: |
RTN4IP1 |
More about : RTN4IP1 |
| Long gene name: |
reticulon 4 interacting protein 1 |
| Locus: |
6q21 |
| Discovery year: |
2002-05-23 |
| GenBank acession: |
AF336861 |
| Entrez gene record: |
84816 |
| Havana BLAST/BLAT: |
OTTHUMG00000015304 |