| Long name: |
Cy5, 5 Conjugated, ARRDC4 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Cy5, 5, 5, Cy5 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
ARRDC4 |
| Specificity: |
This is a highly specific antibody against ARRDC4 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human ARRDC4 |
| Gene ID number: |
91947 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Arrestins are part of a conserved two step mechanism for regulating the activity of G-protein coupled receptors (GPCRs), Different arrestins (visual arrestin (or Arrestin 1), GPCRs activate a heterotrimeric G protein, In order to turn off this response, In response to a stimulus, Once arrestin is bound to the receptor it is unable to signal further, Recent research continues to expand the known actions of arrestins, The arrestins are a family of proteins that are important for regulating signal transduction within cells, The first step is phosphorylation by a class of serine/threonine kinases called G protein coupled receptor kinases (GRKs), This phosphorylation specifically marks the activated receptor for arrestin binding, activated receptors need to be silenced, beta-arrestin 1 (or Arrestin 2) and beta-arrestin 2 (or Arrestin 3) can reduce the activity of their target GPCRs in several different ways, or adapt to a constant stimulus, which can bind to other classes of receptors and can directly activate signaling pathways on their own, ARRDC4 belongs to the arrestin family |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
675nm/694nm |
| Synonyms: |
FLJ36045 |
| Properties: |
Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: |
These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths |
| Gene target: |
ARRDC4 Conjugated |
| Short name: |
Conjugated, ARRDC4 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
5, Cy5 |
| Alternative name: |
cyanine 5, 5 coupled, ARRDC4 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
28087 |
| Gene: |
ARRDC4 |
More about : ARRDC4 |
| Long gene name: |
arrestin domain containing 4 |
| Locus: |
15q26, 2 |
| Discovery year: |
2004-02-11 |
| GenBank acession: |
BC028704 |
| Entrez gene record: |
91947 |
| Pubmed identfication: |
12477932 |
| RefSeq identity: |
NM_183376 |
| Classification: |
Alpha arrestins |
| Havana BLAST/BLAT: |
OTTHUMG00000149849 |