ARRDC4 Antibody

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Catalog number: bs-8078R
Price: 2382 €
Supplier: MBS Recombinant Proteins
Product name: ARRDC4 Antibody
Quantity: 1000ug
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More details :

Long name: ARRDC4 Primary Polyclonal Antibody
Also known as: ARRDC4 PAb
Category: Primary Antibodies
Conjugation: Unconjugated
Target Antigen: ARRDC4
Specificity: This is a highly specific antibody against ARRDC4
Modification(s): None
Modification site(s): Unmodified antibody
Clonality: Polyclonal antibody
Clone number: Polyclonal antibody
Concentration: 1ug per 1ul
Source: This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ARRDC4
Gene ID number: 91947
Tested Applications: IF(IHC-P), IHC-P, WB
Recommended dilutions: IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity: Mouse, Rat, Human
Cross reactive species details: not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen: Arrestins are part of a conserved two step mechanism for regulating the activity of G-protein coupled receptors (GPCRs), Different arrestins (visual arrestin (or Arrestin 1), GPCRs activate a heterotrimeric G protein, In order to turn off this response, In response to a stimulus, Once arrestin is bound to the receptor it is unable to signal further, Recent research continues to expand the known actions of arrestins, The arrestins are a family of proteins that are important for regulating signal transduction within cells, The first step is phosphorylation by a class of serine/threonine kinases called G protein coupled receptor kinases (GRKs), This phosphorylation specifically marks the activated receptor for arrestin binding, activated receptors need to be silenced, beta-arrestin 1 (or Arrestin 2) and beta-arrestin 2 (or Arrestin 3) can reduce the activity of their target GPCRs in several different ways, or adapt to a constant stimulus, which can bind to other classes of receptors and can directly activate signaling pathways on their own, ARRDC4 belongs to the arrestin family
Purification method: This antibody was purified via Protein A
Storage conditions: 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names: ARRD4_HUMAN, Arrestin domain containing protein 4, ARRDC 4
Properties: C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene target: ARRDC4
Short name: ARRDC4 Antibody
Technique: antibodies against human proteins, antibodies for, Antibody
Alternative name: ARRDC4 (Antibody to)
Alternative technique: antibodies
Identity: 28087
Gene: ARRDC4 | More about : ARRDC4
Long gene name: arrestin domain containing 4
Synonyms: FLJ36045
Locus: 15q26, 2
Discovery year: 2004-02-11
GenBank acession: BC028704
Entrez gene record: 91947
Pubmed identfication: 12477932
RefSeq identity: NM_183376
Classification: Alpha arrestins
Havana BLAST/BLAT: OTTHUMG00000149849

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