| Long name: |
ALEXA FLUOR 350 Conjugated, AICDA Polyclonal Antibody |
| Also known as: |
Anti-AICDA PAb ALEXA FLUOR 350 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
350, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
AICDA |
| Specificity: |
This is a highly specific antibody against AICDA |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
140-190/198 |
| Subcellular location: |
Nucleus, Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human AICDA |
| Gene ID Number: |
57379 |
| Swiss Prot: |
Q9GZX7 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Involved in somatic hypermutation, May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation, Required for several crucial steps of B-cell terminal differentiation necessary for efficient antibody responses, and class-switch recombination in B-lymphocytes, gene conversion, Single-stranded DNA-specific cytidine deaminase |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
343nm/442nm |
| Synonyms: |
HIGM2 CDA2 ARP2 AID |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 350, Alexa Fluor |
| Gene target: |
AICDA |
| Short name: |
AICDA Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 350 |
| Alternative name: |
ALEXA FLUOR 350, activation-induced cytidine deaminase (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
AICDA and IDBG-17253 and ENSG00000111732 and 57379, Aicda and IDBG-185563 and ENSMUSG00000040627 and 11628, BT, acting on carbon-nitrogen (but not peptide) bonds, acting on carbon-nitrogen (but not peptide) bonds, acting on carbon-nitrogen (but not peptide) bonds, hydrolase activity, in cyclic amidines, in cyclic amidines, in cyclic amidines and molecular function this GO :0030183 and B cell differentiation and biological process this GO :0045087 and innate immune response and biological process this GO :0045190 and isotype switching and biological process this GO :0071222 and cellular response to lipopolysaccharide and biological process this GO :0080111 and DNA demethylation and biological process this GO :0090310 and negative regulation of methylation-dependent chromatin silencing and biological process, nuclei, this GO :0000178 and exosome (RNase complex) and cellular component this GO :0003824 and catalytic activity and molecular function this GO :0004126 and cytidine deaminase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006397 and mRNA processing and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0009972 and cytidine deamination and biological process this GO :0016445 and somatic diversification of immunoglobulins and biological process this GO :0016446 and somatic hypermutation of immunoglobulin genes and biological process this GO :0016814 and hydrolase activity, this GO :0003824 : catalytic activity, this GO :0003824 : catalytic activity and also this GO :0004126 : cytidine deaminase activity and also this GO :0005515 : protein binding and also this GO :0008270 : zinc ion binding and also this GO :0016814 : hydrolase activity, this GO :0004126 : cytidine deaminase activity, this GO :0005515 : protein binding, this GO :0008270 : zinc ion binding, this GO :0016814 : hydrolase activity, 56893 and IDBG-639763 and ENSBTAG00000018849 and 539888, activation-induced cytidine deaminase |
| Identity: |
13203 |
| Gene: |
AICDA |
More about : AICDA |
| Long gene name: |
activation induced cytidine deaminase |
| Synonyms gene name: |
activation-induced cytidine deaminase |
| Locus: |
12p13, 31 |
| Discovery year: |
2000-09-19 |
| GenBank acession: |
AB040430 |
| Entrez gene record: |
57379 |
| RefSeq identity: |
NM_020661 |
| Classification: |
Apolipoprotein B mRNA editing enzyme catalytic subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000168676 |
| Locus Specific Databases: |
AICDA base: Mutation registry for Aid deficiency LRG_17 |