| Long name: |
FITC Conjugated, AICDA Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
AICDA |
| Specificity: |
This is a highly specific antibody against AICDA |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
140-190/198 |
| Subcellular location: |
Nucleus, Cytoplasm |
| Source: |
KLH conjugated synthetic peptide derived from human AICDA |
| Gene ID number: |
57379 |
| Swiss Prot: |
Q9GZX7 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Involved in somatic hypermutation, May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation, Required for several crucial steps of B-cell terminal differentiation necessary for efficient antibody responses, and class-switch recombination in B-lymphocytes, gene conversion, Single-stranded DNA-specific cytidine deaminase |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
HIGM2 CDA2 ARP2 AID |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
AICDA Conjugated |
| Short name: |
FITC Conjugated, AICDA Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, activation-induced cytidine deaminase (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
AICDA and IDBG-17253 and ENSG00000111732 and 57379, Aicda and IDBG-185563 and ENSMUSG00000040627 and 11628, BT, acting on carbon-nitrogen (but not peptide) bonds, acting on carbon-nitrogen (but not peptide) bonds, acting on carbon-nitrogen (but not peptide) bonds, hydrolase activity, in cyclic amidines, in cyclic amidines, in cyclic amidines and molecular function this GO :0030183 and B cell differentiation and biological process this GO :0045087 and innate immune response and biological process this GO :0045190 and isotype switching and biological process this GO :0071222 and cellular response to lipopolysaccharide and biological process this GO :0080111 and DNA demethylation and biological process this GO :0090310 and negative regulation of methylation-dependent chromatin silencing and biological process, nuclei, this GO :0000178 and exosome (RNase complex) and cellular component this GO :0003824 and catalytic activity and molecular function this GO :0004126 and cytidine deaminase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006397 and mRNA processing and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0009972 and cytidine deamination and biological process this GO :0016445 and somatic diversification of immunoglobulins and biological process this GO :0016446 and somatic hypermutation of immunoglobulin genes and biological process this GO :0016814 and hydrolase activity, this GO :0003824 : catalytic activity, this GO :0003824 : catalytic activity and also this GO :0004126 : cytidine deaminase activity and also this GO :0005515 : protein binding and also this GO :0008270 : zinc ion binding and also this GO :0016814 : hydrolase activity, this GO :0004126 : cytidine deaminase activity, this GO :0005515 : protein binding, this GO :0008270 : zinc ion binding, this GO :0016814 : hydrolase activity, 56893 and IDBG-639763 and ENSBTAG00000018849 and 539888, activation-induced cytidine deaminase |
| Identity: |
13203 |
| Gene: |
AICDA |
More about : AICDA |
| Long gene name: |
activation induced cytidine deaminase |
| Synonyms gene name: |
activation-induced cytidine deaminase |
| Locus: |
12p13, 31 |
| Discovery year: |
2000-09-19 |
| GenBank acession: |
AB040430 |
| Entrez gene record: |
57379 |
| RefSeq identity: |
NM_020661 |
| Classification: |
Apolipoprotein B mRNA editing enzyme catalytic subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000168676 |
| Locus Specific Databases: |
AICDA base: Mutation registry for Aid deficiency LRG_17 |