| Long name: |
ALEXA FLUOR 488 Conjugated, KLHL13 Polyclonal Antibody |
| Also known as: |
Anti-KLHL13 PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
KLHL13 |
| Specificity: |
This is a highly specific antibody against KLHL13 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human KLHL13 |
| Gene ID Number: |
90293 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
E3 ligases accept a ubiquitin residue from an E2 ubiquitin conjugating enzyme and immediately transfer that residue to a protein that is targeted for degradation, Expressed predominantly in brain, KLHL13 interacts with KLHL9 and CUL3, KLHL13 is believed to play a role in protein ubiquitination and may function as a substrate specific adapter of an E3 ubiquitin protein ligase complex, KLHL13 is thought to play a role in spatially orientating substrates in the CUL3 ligase, Specifically, Via its BTB and C terminal Kelch (BACK) motif, a member of the cullin family of mediators that participate in the selective targeting of proteins for ubiquitin mediated proteolysis, also known as BKLHD2 (BTB and kelch domain containing protein 2), is a 604 amino acid protein that contains six Kelch repeats and one BTB/POZ domain, KLHL13 (kelch like 13) |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
FLJ10262 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the KLHL13 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
KLHL13 |
| Short name: |
KLHL13 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, kelch-like 13 (Drosophila) (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
KLHL13 and IDBG-629488 and ENSBTAG00000000501 and 528138, KLHL13 and IDBG-83132 and ENSG00000003096 and 90293, Klhl13 and IDBG-136215 and ENSMUSG00000036782 and 67455, multiple, protein binding, this GO :0000910 and cytokinesis and biological process this GO :0004842 and ubiquitin-protein transferase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0007067 and mitotic nuclear division and biological process this GO :0016567 and protein ubiquitination and biological process this GO :0031463 and Cul3-RING ubiquitin ligase complex and cellular component, this GO :0004842 : ubiquitin-protein transferase activity, this GO :0004842 : ubiquitin-protein transferase activity and also this GO :0005515 : protein binding, this GO :0005515 : protein binding, kelch-like 13 (Drosophila) |
| Identity: |
22931 |
| Gene: |
KLHL13 |
More about : KLHL13 |
| Long gene name: |
kelch like family member 13 |
| Synonyms gene: |
BKLHD2 KIAA1309 |
| Synonyms gene name: |
BTB and kelch domain containing 2, KIAA1309 kelch-like 13 (Drosophila) |
| Locus: |
Xq24 |
| Discovery year: |
2003-07-23 |
| GenBank acession: |
AB037730 |
| Entrez gene record: |
90293 |
| Pubmed identfication: |
10718198 |
| RefSeq identity: |
NM_033495 |
| Classification: |
BTB domain containing Kelch like |
| Havana BLAST/BLAT: |
OTTHUMG00000022252 |
| Locus Specific Databases: |
Mental Retardation database |