| Long name: |
ALEXA FLUOR 647 Conjugated, DNase I Polyclonal Antibody |
| Also known as: |
Anti-DNase I PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
DNase I |
| Specificity: |
This is a highly specific antibody against DNase I |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DNase I |
| Gene ID Number: |
1773 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
A DNase I-like enzyme appears to catalyze the degradation of chromatin to oligo- and mononucleosomes during apoptosis, A recent study has demonstrated an endonuclease with activity and antigenicity indistinguishable from DNase I in thymocytes, DNase I attacks each strand of DNA independently and the cleavage sites are random, DNase I is a Ca2+ and Mg2+ dependant endonuclease, DNase I is an endonuclease that hydrolyzes double-stranded or single stranded DNA preferentially at sites adjacent to pyrimidine nucleotides, DNase I is synthesized in the pancreas and stored in zymogen granules, In the form of a bovine pancreatic enzyme preparation, In the presence of Mg ion, It has been used to reduce the viscosity of cystic fibrosis sputum, The product of hydrolysis is a complex mixture of 5'-phosphate mononucleotides and oligonucleotides, and it was the first DNase for which a specific protein inhibitor was characterized, cells susceptible to apoptosis, it occupies an important place in the history of protein chemistry and enzymology: it was the first enzyme to be recognized as specific for DNA, it was the first DNase to be crystallized, 2 kb long with 9 exons separated by 8 introns, Deoxyribonuclease I gene is approximately 3 |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
DNAS1L3 LSD |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the DNase I Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
DNase I |
| Short name: |
DNase I Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, DNase I (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
2959 |
| Gene: |
DNASE1L3 |
More about : DNASE1L3 |
| Long gene name: |
deoxyribonuclease 1 like 3 |
| Synonyms gene name: |
deoxyribonuclease I like 3 |
| Synonyms name: |
DNase gamma |
| Locus: |
3p14, 3 |
| Discovery year: |
1997-05-15 |
| GenBank acession: |
AF047354 |
| Entrez gene record: |
1776 |
| Pubmed identfication: |
9205125 9714828 14646506 |
| RefSeq identity: |
NM_004944 |
| Havana BLAST/BLAT: |
OTTHUMG00000159153 |