| Catalog number: | bs-7651R-A350 |
|---|---|
| Price: | 553 € |
| Supplier: | MBS Polyclonals_1 |
| Product name: | DNase I Antibody, ALEXA FLUOR 350 |
| Quantity: | 100ug |
| Related search: |
| Long name: | ALEXA FLUOR 350 Conjugated, DNase I Polyclonal Antibody |
|---|---|
| Also known as: | Anti-DNase I PAb ALEXA FLUOR 350 |
| Category: | Conjugated Primary Antibodies |
| Conjugated with: | 350, ALEXA FLUOR® |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | DNase I |
| Specificity: | This is a highly specific antibody against DNase I |
| Modification: | Unmodified |
| Modification Site: | None |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Source: | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DNase I |
| Gene ID Number: | 1773 |
| Tested applications: | IF(IHC-P) |
| Recommended dilutions: | IF(IHC-P)(1:50-200) |
| Crossreactivity: | Mouse, Rat, Human |
| Cross-reactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: | A DNase I-like enzyme appears to catalyze the degradation of chromatin to oligo- and mononucleosomes during apoptosis, A recent study has demonstrated an endonuclease with activity and antigenicity indistinguishable from DNase I in thymocytes, DNase I attacks each strand of DNA independently and the cleavage sites are random, DNase I is a Ca2+ and Mg2+ dependant endonuclease, DNase I is an endonuclease that hydrolyzes double-stranded or single stranded DNA preferentially at sites adjacent to pyrimidine nucleotides, DNase I is synthesized in the pancreas and stored in zymogen granules, In the form of a bovine pancreatic enzyme preparation, In the presence of Mg ion, It has been used to reduce the viscosity of cystic fibrosis sputum, The product of hydrolysis is a complex mixture of 5'-phosphate mononucleotides and oligonucleotides, and it was the first DNase for which a specific protein inhibitor was characterized, cells susceptible to apoptosis, it occupies an important place in the history of protein chemistry and enzymology: it was the first enzyme to be recognized as specific for DNA, it was the first DNase to be crystallized, 2 kb long with 9 exons separated by 8 introns, Deoxyribonuclease I gene is approximately 3 |
| Purification: | Purified by Protein A |
| Storage conditions: | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: | 343nm/442nm |
| Synonyms: | DNAS1L3 LSD |
| Properties: | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: | ALEXA FLUOR 350, Alexa Fluor |
| Gene target: | DNase I |
| Short name: | DNase I Antibody |
| Technique: | antibodies against human proteins, antibodies for, Antibody |
| Label: | ALEXA FLUOR 350 |
| Alternative name: | ALEXA FLUOR 350, DNase I (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 2959 |
| Gene: | DNASE1L3 | More about : DNASE1L3 |
| Long gene name: | deoxyribonuclease 1 like 3 |
| Synonyms gene name: | deoxyribonuclease I like 3 |
| Synonyms name: | DNase gamma |
| Locus: | 3p14, 3 |
| Discovery year: | 1997-05-15 |
| GenBank acession: | AF047354 |
| Entrez gene record: | 1776 |
| Pubmed identfication: | 9205125 9714828 14646506 |
| RefSeq identity: | NM_004944 |
| Havana BLAST/BLAT: | OTTHUMG00000159153 |
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