| Long name: |
ALEXA FLUOR 488 Conjugated, VDAC Polyclonal Antibody |
| Also known as: |
VDAC2, VDAC3 PAb ALEXA FLUOR 488, Anti-VDAC1 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
VDAC2, VDAC3, VDAC1 |
| Specificity: |
VDAC2, VDAC3, This is a highly specific antibody against VDAC1 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human VDAC3 |
| Gene ID Number: |
7419 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
It adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV, May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis, The channel at the outer mitochondrial membrane allows diffusion of small hydrophilic molecules, The open state has a weak anion selectivity whereas the closed state is cation-selective, in the plasma membrane it is involved in cell volume regulation and apoptosis, Forms a channel through the mitochondrial outer membrane and also the plasma membrane |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
Outer mitochondrial membrane protein porin 3, Porin, VDAC2, hVDAC1, hVDAC3, mVDAC3, voltage dependent anion channel 3, VDAC1 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the VDAC Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
VDAC |
| Short name: |
VDAC Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, VDAC (Antibody to) |
| Alternative technique: |
antibodies |