| Long name: |
VDAC 1 Primary Polyclonal Antibody |
| Also known as: |
VDAC 1 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
VDAC 1 |
| Specificity: |
This is a highly specific antibody against VDAC 1 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Source: |
Synthesis peptide (KLH coupled) corresponding to C-terminal residues of Human VDAC1 |
| Gene ID number: |
7416 |
| Swiss Prot: |
P21796 |
| Tested Applications: |
WB |
| Recommended dilutions: |
WB (1:2000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
It adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV, May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis (PubMed:15033708, PubMed:18755977, PubMed:20230784, PubMed:25296756), PubMed:8420959), The channel at the outer mitochondrial membrane allows diffusion of small hydrophilic molecules, The open state has a weak anion selectivity whereas the closed state is cation-selective (PubMed:11845315, in the plasma membrane it is involved in cell volume regulation and apoptosis, Forms a channel through the mitochondrial outer membrane and also the plasma membrane |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Outer mitochondrial membrane protein porin 1, Plasmalemmal porin, Porin 31HL, Porin 31HM, VDAC, VDAC-1, VDAC1, Voltage-dependent anion-selective channel protein 1, hVDAC1, PORIN |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
VDAC 1 |
| Short name: |
VDAC 1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
VDAC 1 (Antibody to) |
| Alternative technique: |
antibodies |